8UCX
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4ISD
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![BU of 4isd by Molmil](/molmil-images/mine/4isd) | Crystal structure of GLUTATHIONE TRANSFERASE homolog from BURKHOLDERIA GL BGR1, TARGET EFI-501803, with bound glutathione | Descriptor: | GLUTATHIONE, Glutathione S-transferase | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-01-16 | Release date: | 2013-02-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structure of GLUTATHIONE TRANSFERASE homolog from BURKHOLDERIA GL BGR1, TARGET EFI-501803, with bound glutathione TO BE PUBLISHED
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2W1H
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![BU of 2w1h by Molmil](/molmil-images/mine/2w1h) | Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity | Descriptor: | CELL DIVISION PROTEIN KINASE 2, N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE | Authors: | Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. | Deposit date: | 2008-10-17 | Release date: | 2009-01-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity. J.Med.Chem., 52, 2009
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8J4Q
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6NAX
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![BU of 6nax by Molmil](/molmil-images/mine/6nax) | Olfactomedin domain of mouse myocilin | Descriptor: | CALCIUM ION, GLYCEROL, Myocilin, ... | Authors: | Patterson-Orazem, A.C, Hill, S.E, Lieberman, R.L. | Deposit date: | 2018-12-06 | Release date: | 2019-03-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.551 Å) | Cite: | Differential Misfolding Properties of Glaucoma-Associated Olfactomedin Domains from Humans and Mice. Biochemistry, 58, 2019
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5FYK
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![BU of 5fyk by Molmil](/molmil-images/mine/5fyk) | Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade B JR-FL SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22, ... | Authors: | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | Deposit date: | 2016-03-08 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.107 Å) | Cite: | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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2AKY
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5F7W
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![BU of 5f7w by Molmil](/molmil-images/mine/5f7w) | Blood group antigen binding adhesin BabA of Helicobacter pylori strain 17875 in complex with blood group B Lewis b heptasaccharide | Descriptor: | Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H. | Deposit date: | 2015-12-08 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori. Cell Host Microbe, 19, 2016
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1A91
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![BU of 1a91 by Molmil](/molmil-images/mine/1a91) | SUBUNIT C OF THE F1FO ATP SYNTHASE OF ESCHERICHIA COLI; NMR, 10 STRUCTURES | Descriptor: | F1FO ATPASE SUBUNIT C | Authors: | Girvin, M.E, Rastogi, V.K, Abildgaard, F, Markley, J.L, Fillingame, R.H. | Deposit date: | 1998-04-15 | Release date: | 1998-07-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the transmembrane H+-transporting subunit c of the F1F0 ATP synthase. Biochemistry, 37, 1998
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1ADX
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![BU of 1adx by Molmil](/molmil-images/mine/1adx) | FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, 14 STRUCTURES | Descriptor: | THROMBOMODULIN | Authors: | Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A. | Deposit date: | 1997-02-18 | Release date: | 1997-12-24 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern. J.Mol.Biol., 273, 1997
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6SUP
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![BU of 6sup by Molmil](/molmil-images/mine/6sup) | Crystal Structure of TcdB2-TccC3-Cdc42 | Descriptor: | MAGNESIUM ION, TcdB2,TccC3,Cell division control protein 42 homolog | Authors: | Roderer, D, Schubert, E, Sitsel, O, Raunser, S. | Deposit date: | 2019-09-16 | Release date: | 2019-12-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Towards the application of Tc toxins as a universal protein translocation system. Nat Commun, 10, 2019
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2O03
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5CGW
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![BU of 5cgw by Molmil](/molmil-images/mine/5cgw) | CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F | Descriptor: | ACETATE ION, Beta-lactamase, ZINC ION | Authors: | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | Deposit date: | 2015-07-09 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
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6NIZ
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1NOJ
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3JWD
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![BU of 3jwd by Molmil](/molmil-images/mine/3jwd) | Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 48D HEAVY CHAIN, FAB 48D LIGHT CHAIN, ... | Authors: | Pancera, M, Majeed, S, Ban, Y.A, Chen, L, Huang, C.C, Kong, L, Kwon, Y.D, Stuckey, J, Zhou, T, Robinson, J.E, Schief, W.R, Sodroski, J, Wyatt, R, Kwong, P.D. | Deposit date: | 2009-09-18 | Release date: | 2009-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proc.Natl.Acad.Sci.USA, 107, 2010
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6C24
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![BU of 6c24 by Molmil](/molmil-images/mine/6c24) | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | Authors: | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | Deposit date: | 2018-01-06 | Release date: | 2018-01-24 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359, 2018
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6SLK
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![BU of 6slk by Molmil](/molmil-images/mine/6slk) | Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus | Descriptor: | L-2,4-diaminobutyric acid acetyltransferase, SODIUM ION, SULFATE ION | Authors: | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | Deposit date: | 2019-08-20 | Release date: | 2020-01-29 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
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6NNJ
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2WK0
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![BU of 2wk0 by Molmil](/molmil-images/mine/2wk0) | Crystal structure of the class A beta-lactamase BS3 inhibited by 6- beta-iodopenicillanate. | Descriptor: | (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, BETA-LACTAMASE, CHLORIDE ION, ... | Authors: | Sauvage, E, Zervosen, A, Dive, G, Herman, R, Kerff, F, Amoroso, A, Fonze, E, Pratt, R.F, Luxen, A, Charlier, P. | Deposit date: | 2009-06-03 | Release date: | 2009-12-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131, 2009
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4N0T
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![BU of 4n0t by Molmil](/molmil-images/mine/4n0t) | Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution | Descriptor: | SULFATE ION, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA | Authors: | Montemayor, E.J, Curran, E.C, Liao, H, Andrews, K.L, Treba, C.N, Butcher, S.E, Brow, D.A. | Deposit date: | 2013-10-02 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Core structure of the U6 small nuclear ribonucleoprotein at 1.7- angstrom resolution. Nat.Struct.Mol.Biol., 21, 2014
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4ZM5
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![BU of 4zm5 by Molmil](/molmil-images/mine/4zm5) | Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - A107P mutant | Descriptor: | CHLORIDE ION, Chain length determinant protein, MAGNESIUM ION | Authors: | Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R. | Deposit date: | 2015-05-02 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri. Plos One, 10, 2015
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5MOL
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![BU of 5mol by Molmil](/molmil-images/mine/5mol) | Human IgE-Fc crystal structure | Descriptor: | 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, 2-(2-METHOXYETHOXY)ETHANOL, ... | Authors: | Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | Deposit date: | 2016-12-14 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E. Biochim. Biophys. Acta, 1865, 2017
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2O78
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![BU of 2o78 by Molmil](/molmil-images/mine/2o78) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant) complexed with cinnamic acid | Descriptor: | PHENYLETHYLENECARBOXYLIC ACID, Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-10 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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6Z7O
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![BU of 6z7o by Molmil](/molmil-images/mine/6z7o) | Crystal structure of Thioredoxin T from Drosophila melanogaster | Descriptor: | Thioredoxin-T, ZINC ION | Authors: | Freier, R, Aragon, E, Baginski, B, Pluta, R, Martin-Malpartida, P, Torner, C, Gonzaez, C, Macias, M. | Deposit date: | 2020-05-31 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins. Iucrj, 8, 2021
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