5MOL

Human IgE-Fc crystal structure

Summary for 5MOL

• Entry DOI: 10.2210/pdb5mol/pdb
• Descriptor: Ig epsilon chain C region, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: immunoglobulin e, ige-fc, antibodies, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted : P01854
• Total number of polymer chains: 2
• Total formula weight: 75752.54

Authors

Dore, K.A.,Davies, A.M.,Drinkwater, N.,Beavil, A.J.,McDonnell, J.M.,Sutton, B.J. (deposition date: 2016-12-14, release date: 2018-01-10, Last modification date: 2024-01-17)

• Primary citation: Dore, K.A.,Davies, A.M.,Drinkwater, N.,Beavil, A.J.,McDonnell, J.M.,Sutton, B.J.; Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E.; Biochim. Biophys. Acta, 1865:1336-1347, 2017; PubMed: 28844738; DOI: 10.1016/j.bbapap.2017.08.005

Experimental method

X-RAY DIFFRACTION (1.75 Å)