5MOL
Human IgE-Fc crystal structure
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ig epsilon chain C region | polymer | 327 | 36354.8 | 2 | UniProt (P01854) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
2 | C | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G94626GC) | |||
3 | D | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
4 | A, B | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 2 | Chemie (PG0) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
6 | A, B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
7 | B | 2-(2-ETHOXYETHOXY)ETHANOL | non-polymer | 134.2 | 1 | Chemie (AE3) | |||
8 | water | water | 18.0 | 601 | Chemie (HOH) |
Sequence modifications
A, B: 224 - 547 (UniProt: P01854)
PDB | External Database | Details |
---|---|---|
Asp 222 | - | expression tag |
Ile 223 | - | expression tag |
Ala 225 | Cys 105 | conflict |
Gln 265 | Asn 146 | conflict |
Gln 371 | Asn 252 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 72709.6 | |
Branched | Number of molecules | 2 |
Total formula weight | 2145.9 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 897.0 | |
All* | Total formula weight | 75752.5 |