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3FH6
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BU of 3fh6 by Molmil
Crystal structure of the resting state maltose transporter from E. coli
Descriptor: Maltose transport system permease protein malF, Maltose transport system permease protein malG, Maltose/maltodextrin import ATP-binding protein malK
Authors:Khare, D, Oldham, M.L, Orelle, C, Davidson, A.L, Chen, J.
Deposit date:2008-12-08
Release date:2009-03-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Alternating access in maltose transporter mediated by rigid-body rotations.
Mol.Cell, 33, 2009
3FHT
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BU of 3fht by Molmil
Crystal structure of human Dbp5 in complex with AMPPNP and RNA
Descriptor: ATP-dependent RNA helicase DDX19B, GLYCEROL, MAGNESIUM ION, ...
Authors:von Moeller, H, Conti, E.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
Nat.Struct.Mol.Biol., 16, 2009
3OYK
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BU of 3oyk by Molmil
Crystal structure of the PFV S217H mutant intasome bound to manganese
Descriptor: AMMONIUM ION, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ...
Authors:Hare, S, Cherepanov, P.
Deposit date:2010-09-23
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OM3
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BU of 3om3 by Molmil
Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation in the reduced state
Descriptor: (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ...
Authors:Liu, J, Qin, L, Ferguson-Miller, S.
Deposit date:2010-08-26
Release date:2011-02-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
3F40
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BU of 3f40 by Molmil
Crystal structure of NTF2-like protein of unknown function (YP_677363.1) from CYTOPHAGA HUTCHINSONII ATCC 33406 at 1.27 A resolution
Descriptor: uncharacterized NTF2-like protein
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-10-31
Release date:2008-11-18
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Crystal structure of NTF2-like protein of unknown function (YP_677363.1) from CYTOPHAGA HUTCHINSONII ATCC 33406 at 1.27 A resolution
To be published
3OZI
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BU of 3ozi by Molmil
Crystal structure of the TIR domain from the flax disease resistance protein L6
Descriptor: COBALT (II) ION, L6tr
Authors:Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B.
Deposit date:2010-09-25
Release date:2011-04-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation.
Cell Host Microbe, 9, 2011
3OMG
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BU of 3omg by Molmil
Structure of human SND1 extended tudor domain in complex with the symmetrically dimethylated arginine PIWIL1 peptide R14me2s
Descriptor: Staphylococcal nuclease domain-containing protein 1, dimethylated arginine peptide R14me2s
Authors:Lam, R, Liu, K, Guo, Y.H, Bian, C.B, Xu, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2010-08-26
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
3FJX
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BU of 3fjx by Molmil
E. coli EPSP synthase (T97I) liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E.
Deposit date:2008-12-15
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli.
J.Biol.Chem., 284, 2009
3FLE
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BU of 3fle by Molmil
SE_1780 protein of unknown function from Staphylococcus epidermidis.
Descriptor: SE_1780 protein
Authors:Osipiuk, J, Hatzos, C, Clancy, S, Kim, Y, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-12-18
Release date:2009-01-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:X-ray crystal structure of SE_1780 protein of unknown function from Staphylococcus epidermidis.
To be Published
3ONM
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BU of 3onm by Molmil
Effector binding Domain of LysR-Type transcription factor RovM from Y. pseudotuberculosis
Descriptor: Transcriptional regulator LrhA
Authors:Quade, N, Diekmann, M, Haffke, M, Heroven, A.K, Dersch, P, Heinz, D.W.
Deposit date:2010-08-30
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis.
Acta Crystallogr.,Sect.D, 67, 2011
3F4S
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BU of 3f4s by Molmil
Crystal structure of Wolbachia pipientis alpha-DsbA1 T172V
Descriptor: Putative uncharacterized protein, TRIETHYLENE GLYCOL
Authors:Kurz, M, Heras, B, Martin, J.L.
Deposit date:2008-11-02
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural and Functional Characterization of the Oxidoreductase alpha-DsbA1 from Wolbachia pipientis
ANTIOXID.REDOX SIGNAL., 11, 2009
3P10
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BU of 3p10 by Molmil
Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol
Descriptor: (2-thiophen-2-ylphenyl)methanol, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-09-29
Release date:2010-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3FLP
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BU of 3flp by Molmil
Crystal structure of native heptameric SAP-like pentraxin from Limulus polyphemus
Descriptor: CALCIUM ION, SAP-like pentraxin
Authors:Shrive, A.K, Greenhough, T.J, Armstrong, P.B.
Deposit date:2008-12-19
Release date:2009-01-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of Limulus SAP-like pentraxin reveal two molecular aggregations.
J.Mol.Biol., 386, 2009
3FMZ
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BU of 3fmz by Molmil
Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand
Descriptor: 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid, Retinol-binding protein 4
Authors:Wang, Z, Johnstone, S, Walker, N.P.
Deposit date:2008-12-22
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo.
J.Biol.Chem., 284, 2009
3OO8
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BU of 3oo8 by Molmil
Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose
Descriptor: ABC transporter binding protein AcbH, GLYCEROL, SULFATE ION
Authors:Vahedi-Faridi, A, Bulut, H, Licht, A.
Deposit date:2010-08-30
Release date:2010-12-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose
J.Mol.Biol., 406, 2011
3P2E
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BU of 3p2e by Molmil
Structure of an antibiotic related Methyltransferase
Descriptor: 16S rRNA methylase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Sivaraman, J, Husain, N.
Deposit date:2010-10-02
Release date:2010-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Nucleic Acids Res., 2010
3F6H
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BU of 3f6h by Molmil
Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III
Descriptor: Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION
Authors:Zhang, P, Ma, J, Zhao, G, Ding, J.
Deposit date:2008-11-06
Release date:2009-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
3F43
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BU of 3f43 by Molmil
Crystal structure of a putative anti-sigma factor antagonist (tm1081) from thermotoga maritima at 1.59 A resolution
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-10-31
Release date:2008-11-25
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal structure of Putative anti-sigma factor antagonist TM1081 (TM1081) from THERMOTOGA MARITIMA at 1.59 A resolution
To be published
3F4T
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BU of 3f4t by Molmil
Crystal structure of Wolbachia pipientis alpha-DsbA1 C97A/C146A
Descriptor: PENTAETHYLENE GLYCOL, Putative uncharacterized protein, TRIETHYLENE GLYCOL
Authors:Kurz, M, Heras, B, Martin, J.L.
Deposit date:2008-11-02
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Functional Characterization of the Oxidoreductase alpha-DsbA1 from Wolbachia pipientis
ANTIOXID.REDOX SIGNAL., 11, 2009
3P3T
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BU of 3p3t by Molmil
Human transthyretin (TTR) complexed with 4-(3-(2-flourophenoxy)propyl)-3,5-dimethyl-1H-pyrazole
Descriptor: 4-[3-(2-fluorophenoxy)propyl]-3,5-dimethyl-1H-pyrazole, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2010-10-05
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
3F6U
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BU of 3f6u by Molmil
Crystal structure of human Activated Protein C (APC) complexed with PPACK
Descriptor: CALCIUM ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, ...
Authors:Schmidt, A.E, Padmanabhan, K, Underwood, M.C, Bode, W, Mather, T, Bajaj, S.P.
Deposit date:2008-11-06
Release date:2008-11-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC).
J.Biol.Chem., 277, 2002
3OQK
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BU of 3oqk by Molmil
Crystal Structure Analysis of Renin-indole-piperazin inhibitor complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-phenoxy-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indole, GLYCEROL, ...
Authors:Bocskei, Z.
Deposit date:2010-09-03
Release date:2010-10-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3P45
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BU of 3p45 by Molmil
Crystal structure of apo-caspase-6 at physiological pH
Descriptor: caspase-6
Authors:Mueller, I, Lamers, M.B.A.C, Ritchie, A.J, Dominguez, C, Munoz, I, Maillard, M, Kiselyov, A.
Deposit date:2010-10-06
Release date:2011-06-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structures of active and inhibitor-bound human Casp6
To be Published
3F79
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BU of 3f79 by Molmil
Structure of pseudo-centered cell crystal form of the C-terminal phosphatase domain of P. aeruginosa RssB
Descriptor: MAGNESIUM ION, Probable two-component response regulator
Authors:Levchenko, I, Grant, R.A, Sauer, R.T, Baker, T.A.
Deposit date:2008-11-07
Release date:2009-11-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of RSSB, a CLPX adaptor protein that regulates sigma S
To be Published
3P5A
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BU of 3p5a by Molmil
Human Carbonic Anhydrase complexed with Sodium morpholinocarbodithioate
Descriptor: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ...
Authors:Aggarwal, M, McKenna, R.
Deposit date:2010-10-08
Release date:2011-10-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo
J.Med.Chem., 55, 2012

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数据于2024-10-02公开中

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