3P45

Crystal structure of apo-caspase-6 at physiological pH

Summary for 3P45

• Entry DOI: 10.2210/pdb3p45/pdb
• Descriptor: caspase-6 (3 entities in total)
• Functional Keywords: protease, huntington's disease, mature apo-caspase-6, physiological ph, competitive inhibition, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P55212 P55212
• Total number of polymer chains: 16
• Total formula weight: 263004.18

Authors

Mueller, I.,Lamers, M.B.A.C.,Ritchie, A.J.,Dominguez, C.,Munoz, I.,Maillard, M.,Kiselyov, A. (deposition date: 2010-10-06, release date: 2011-06-15, Last modification date: 2024-02-21)

• Primary citation: Mueller, I.,Lamers, M.B.A.C.,Ritchie, A.J.,Dominquez, C.,Munoz, I.,Maillard, M.,Kiselyov, A.; Crystal structures of active and inhibitor-bound human Casp6; To be Published,

Experimental method

X-RAY DIFFRACTION (2.53 Å)