3P45

Crystal structure of apo-caspase-6 at physiological pH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	caspase-6	polymer	179	20474.3	8	UniProt (P55212) Pfam (PF00656)	Homo sapiens (human)
2	B, D, F, H, J... (B, D, F, H, J...)	caspase-6	polymer	108	12401.2	8	UniProt (P55212) Pfam (PF00656)	Homo sapiens (human)
3	AA, BA, CA, DA, EA... (K, L, M, N, O...)	water	water		18.0	201	Chemie (HOH)

Sequence modifications

B, D, F, H, J, L, N, P: 193 - 293 (UniProt: P55212)

PDB	External Database	Details
Arg 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	263004.2
All*	Total formula weight	263004.2

*Water molecules are not included.