1R5V
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![BU of 1r5v by Molmil](/molmil-images/mine/1r5v) | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation | Descriptor: | H-2 class II histocompatibility antigen, E-K alpha chain, MHC H2-IE-beta, ... | Authors: | Krogsgaard, M, Prado, N, Adams, E.J, He, X.L, Chow, D.C, Wilson, D.B, Garcia, K.C, Davis, M.M. | Deposit date: | 2003-10-13 | Release date: | 2004-02-03 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation. Mol.Cell, 12, 2003
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4H26
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![BU of 4h26 by Molmil](/molmil-images/mine/4h26) | TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | Deposit date: | 2012-09-12 | Release date: | 2013-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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1RIH
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![BU of 1rih by Molmil](/molmil-images/mine/1rih) | Crystal Structure of Fab 14F7, a unique anti-tumor antibody specific for N-glycolyl GM3 | Descriptor: | heavy chain of antibody 14F7, light chain of antibody 14F7 | Authors: | Krengel, U, Olsson, L.-L, Martinez, C, Talavera, A, Rojas, G, Mier, E, Angstrom, J, Moreno, E. | Deposit date: | 2003-11-17 | Release date: | 2004-01-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3. J.Biol.Chem., 279, 2004
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7CPO
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![BU of 7cpo by Molmil](/molmil-images/mine/7cpo) | Crystal Structure of Anolis carolinensis MHC I complex | Descriptor: | HIS-VAL-TYR-GLY-PRO-LEU-LYS-PRO-ILE, MHC CLASS I ANTIGEN, beta2-microglobulin | Authors: | Wang, Y, Qu, Z, Ma, L, Wei, X, Zhang, N, Xia, C. | Deposit date: | 2020-08-07 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Crystal Structure of the MHC Class I (MHC-I) Molecule in the Green Anole Lizard Demonstrates the Unique MHC-I System in Reptiles. J Immunol., 206, 2021
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2SEB
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![BU of 2seb by Molmil](/molmil-images/mine/2seb) | X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH A PEPTIDE FROM HUMAN COLLAGEN II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENTEROTOXIN TYPE B, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Dessen, A, Lawrence, C.M, Cupo, S, Zaller, D.M, Wiley, D.C. | Deposit date: | 1997-10-16 | Release date: | 1998-01-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II. Immunity, 7, 1997
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5XJF
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![BU of 5xjf by Molmil](/molmil-images/mine/5xjf) | Crystal structure of fucosylated IgG Fc Y296W mutant complexed with bis-glycosylated soluble form of Fc gamma receptor IIIa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Sakae, Y, Satoh, T, Yagi, H, Yanaka, S, Yamaguchi, T, Isoda, Y, Iida, S, Okamoto, Y, Kato, K. | Deposit date: | 2017-05-01 | Release date: | 2017-11-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational effects of N-glycan core fucosylation of immunoglobulin G Fc region on its interaction with Fc gamma receptor IIIa. Sci Rep, 7, 2017
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4UDU
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![BU of 4udu by Molmil](/molmil-images/mine/4udu) | Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | Descriptor: | ENTEROTOXIN TYPE E, PROTEIN TRBV7-9, T-CELL RECEPTOR BETA-2 CHAIN C REGION, ... | Authors: | Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K. | Deposit date: | 2014-12-11 | Release date: | 2015-06-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Staphylococcal Enterotoxin E in Complex with Tcr Defines the Role of Tcr Loop Positioning in Superantigen Recognition. Plos One, 10, 2015
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3EYO
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![BU of 3eyo by Molmil](/molmil-images/mine/3eyo) | Crystal structure of anti-human cytomegalovirus antibody 8F9 | Descriptor: | 8f9 Fab, AD-2 | Authors: | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | Deposit date: | 2008-10-21 | Release date: | 2008-12-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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6RPB
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![BU of 6rpb by Molmil](/molmil-images/mine/6rpb) | Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | Deposit date: | 2019-05-14 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
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2RFX
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![BU of 2rfx by Molmil](/molmil-images/mine/2rfx) | Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J. | Deposit date: | 2007-10-02 | Release date: | 2008-07-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity, 28, 2008
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4Y19
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![BU of 4y19 by Molmil](/molmil-images/mine/4y19) | immune complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FS18_alpha, FS18_beta, ... | Authors: | Beringer, D.X, Petersen, J, Reid, H.H, Rossjohn, J. | Deposit date: | 2015-02-07 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nat.Immunol., 16, 2015
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2J4W
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![BU of 2j4w by Molmil](/molmil-images/mine/2j4w) | Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex | Descriptor: | APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19 | Authors: | Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | Deposit date: | 2006-09-07 | Release date: | 2007-01-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation. J.Mol.Biol., 366, 2007
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4HUV
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![BU of 4huv by Molmil](/molmil-images/mine/4huv) | Crystal Structure of H2Db-NPM6W | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Gras, S, Twist, K.A, Rossjohn, J. | Deposit date: | 2012-11-04 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proc.Natl.Acad.Sci.USA, 110, 2013
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2MHA
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![BU of 2mha by Molmil](/molmil-images/mine/2mha) | CRYSTAL STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I H-2KB MOLECULE CONTAINING A SINGLE VIRAL PEPTIDE: IMPLICATIONS FOR PEPTIDE BINDING AND T-CELL RECEPTOR RECOGNITION | Descriptor: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H-2KB) (ALPHA CHAIN), VIRAL OCTAPEPTIDE ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU | Authors: | Zhang, W, Young, A.C.M, Imarai, M, Nathenson, S.G, Sacchettini, J.C. | Deposit date: | 1993-07-21 | Release date: | 1993-10-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc.Natl.Acad.Sci.USA, 89, 1992
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5U72
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![BU of 5u72 by Molmil](/molmil-images/mine/5u72) | |
1BMG
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![BU of 1bmg by Molmil](/molmil-images/mine/1bmg) | |
3VXM
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![BU of 3vxm by Molmil](/molmil-images/mine/3vxm) | The complex between C1-28 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide | Descriptor: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, C1-28 TCR alpha chain, ... | Authors: | Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A. | Deposit date: | 2012-09-20 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection SCI REP, 3, 2013
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1NCA
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![BU of 1nca by Molmil](/molmil-images/mine/1nca) | REFINED CRYSTAL STRUCTURE OF THE INFLUENZA VIRUS N9 NEURAMINIDASE-NC41 FAB COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, IGG2A-KAPPA NC41 FAB (HEAVY CHAIN), ... | Authors: | Tulip, W.R, Varghese, J.N, Colman, P.M. | Deposit date: | 1992-01-21 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex. J.Mol.Biol., 227, 1992
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6KWK
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![BU of 6kwk by Molmil](/molmil-images/mine/6kwk) | Crystal structure of pSLA-1*0401 complex with FMDV-derived epitope MTAHITVPY | Descriptor: | Beta-2-microglobulin, MHC class I antigen, peptide | Authors: | Wei, X.H, Wang, S, Zhang, N.Z, Xia, C. | Deposit date: | 2019-09-07 | Release date: | 2020-09-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Peptidomes and Structures Illustrate Two Distinguishing Mechanisms of Alternating the Peptide Plasticity Caused by Swine MHC Class I Micropolymorphism. Front Immunol, 12, 2021
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1NCB
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![BU of 1ncb by Molmil](/molmil-images/mine/1ncb) | CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Tulip, W.R, Varghese, J.N, Colman, P.M. | Deposit date: | 1992-01-21 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface. J.Mol.Biol., 227, 1992
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2JCC
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![BU of 2jcc by Molmil](/molmil-images/mine/2jcc) | AH3 recognition of mutant HLA-A2 W167A | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ... | Authors: | Miller, P, Benhar, Y.P, Biddison, W, Collins, E.J. | Deposit date: | 2006-12-21 | Release date: | 2007-10-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding. J.Mol.Biol., 373, 2007
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1FO0
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![BU of 1fo0 by Molmil](/molmil-images/mine/1fo0) | MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX | Descriptor: | NATURALLY PROCESSED OCTAPEPTIDE PBM1, PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), ... | Authors: | Reiser, J.B, Darnault, C, Guimezanes, A, Gregoire, C, Mosser, T, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Malissen, B, Housset, D, Mazza, G. | Deposit date: | 2000-08-24 | Release date: | 2000-10-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat.Immunol., 1, 2000
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7NA5
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![BU of 7na5 by Molmil](/molmil-images/mine/7na5) | Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen | Descriptor: | 47BE7 TCR alpha chain, 47BE7 TCR beta chain, Beta-2-microglobulin, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-19 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI To be Published
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7N2P
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![BU of 7n2p by Molmil](/molmil-images/mine/7n2p) | AS4.3-RNASEH2b-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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1KB5
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![BU of 1kb5 by Molmil](/molmil-images/mine/1kb5) | MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX | Descriptor: | ANTIBODY DESIRE-1, KB5-C20 T-CELL ANTIGEN RECEPTOR | Authors: | Housset, D, Mazza, G, Gregoire, C, Piras, C, Malissen, B, Fontecilla-Camps, J.C. | Deposit date: | 1997-04-06 | Release date: | 1998-04-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. EMBO J., 16, 1997
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