1RIH
Crystal Structure of Fab 14F7, a unique anti-tumor antibody specific for N-glycolyl GM3
Summary for 1RIH
| Entry DOI | 10.2210/pdb1rih/pdb |
| Descriptor | light chain of antibody 14F7, heavy chain of antibody 14F7 (3 entities in total) |
| Functional Keywords | antibody, carbohydrate-binding fab, specific for neugc-gm3, immunoglobulin, beta-sheet topology, immune system |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 48956.42 |
| Authors | Krengel, U.,Olsson, L.-L.,Martinez, C.,Talavera, A.,Rojas, G.,Mier, E.,Angstrom, J.,Moreno, E. (deposition date: 2003-11-17, release date: 2004-01-13, Last modification date: 2023-08-23) |
| Primary citation | Krengel, U.,Olsson, L.-L.,Talavera, A.,Rojas, G.,Mier, E.,Moreno, E. Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3. J.Biol.Chem., 279:5597-5603, 2004 Cited by PubMed: 14627696DOI: 10.1074/jbc.M311693200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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