6JE3
| Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhang | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target DNA strand, ... | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-03 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.931 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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5UTI
| Crystal Structure of TGT in complex with fragment in preQ1 pocket | Descriptor: | DIMETHYL SULFOXIDE, L-CANAVANINE, Queuine tRNA-ribosyltransferase, ... | Authors: | Hassaan, E, Heine, A, Klebe, G. | Deposit date: | 2017-02-15 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15, 2020
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6JFU
| Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target strand, ... | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-12 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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7MEU
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4A5U
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2ESI
| Complex between Kanamycin A and the 16S-Rrna A Site. | Descriptor: | 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', KANAMYCIN A | Authors: | Westhof, E. | Deposit date: | 2005-10-26 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding Nucleic Acids Res., 33, 2005
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3HI9
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1QM9
| NMR, REPRESENTATIVE STRUCTURE | Descriptor: | POLYPYRIMIDINE TRACT-BINDING PROTEIN | Authors: | Conte, M.R, Grune, T, Curry, S, Matthews, S. | Deposit date: | 1999-09-22 | Release date: | 2000-07-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of Tandem RNA Recognition Motifs from Polypyrimidine Tract Binding Protein Reveals Novel Features of the Rrm Fold Embo J., 19, 2000
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2MKD
| Human JAZ ZF3 Residues 168-227 | Descriptor: | ZINC ION, Zinc finger protein 346 | Authors: | Wright, P, Dyson, J, Burge, R, Martinez-Yamout, M. | Deposit date: | 2014-02-05 | Release date: | 2014-03-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of Interactions between the Double-Stranded RNA-Binding Zinc Finger Protein JAZ and Nucleic Acids. Biochemistry, 53, 2014
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2M7S
| NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1 | Descriptor: | Serine/arginine-rich splicing factor 1 | Authors: | Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) | Deposit date: | 2013-04-29 | Release date: | 2013-05-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1 To be Published
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4MFR
| Crystal structure of Mycobacterium tuberculosis CarD | Descriptor: | GLYCEROL, IODIDE ION, RNA polymerase-binding transcription factor CarD, ... | Authors: | Kaur, G, Thakur, K.G. | Deposit date: | 2013-08-28 | Release date: | 2013-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis CarD, an essential RNA polymerase binding protein, reveals a quasidomain-swapped dimeric structural architecture. Proteins, 82, 2014
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6WC0
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1U09
| Footand Mouth Disease Virus RNA-dependent RNA polymerase | Descriptor: | polyprotein | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2004-07-13 | Release date: | 2004-08-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
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6B91
| Crystal structure of the N-terminal domain of human METTL16 | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | Authors: | Ruszkowska, A, Ruszkowski, M, Dauter, Z, Brown, J.A. | Deposit date: | 2017-10-09 | Release date: | 2018-04-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural insights into the RNA methyltransferase domain of METTL16. Sci Rep, 8, 2018
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6AHE
| Crystal structure of enoyl-ACP reductase from Acinetobacter baumannii in complex with NAD and AFN-1252 | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Rani, S.T, Nataraj, V, Laxminarasimhan, A, Thomas, A, Krishnamurthy, N. | Deposit date: | 2018-08-17 | Release date: | 2019-08-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Ternary complex formation of AFN-1252 with Acinetobacter baumannii FabI and NADH: Crystallographic and biochemical studies. Chem.Biol.Drug Des., 96, 2020
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2DGQ
| Solution structure of the N-terminal RNA binding domain in Bruno-like 6 RNA-binding protein | Descriptor: | bruno-like 6, RNA binding protein | Authors: | Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-15 | Release date: | 2006-09-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal RNA binding domain in Bruno-like 6 RNA-binding protein To be Published
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2DMY
| Solution structure of DSRM domain in Spermatid perinuclear RNA-bind protein | Descriptor: | Spermatid perinuclear RNA-binding protein | Authors: | Kadirvel, S, He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-24 | Release date: | 2006-10-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of DSRM domain in Spermatid perinuclear RNA-bind protein To be Published
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1NTB
| 2.9 A crystal structure of Streptomycin RNA-aptamer complex | Descriptor: | 5'-R(*CP*GP*GP*CP*AP*CP*CP*AP*CP*GP*GP*UP*CP*GP*GP*AP*UP*C)-3', 5'-R(*GP*GP*AP*UP*CP*GP*CP*AP*UP*UP*UP*GP*GP*AP*CP*UP*UP*CP*UP*GP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Tereshko, V, Skripkin, E, Patel, D.J. | Deposit date: | 2003-01-29 | Release date: | 2003-05-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Encapsulating Streptomycin within a small 40-mer RNA CHEM.BIOL., 10, 2003
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6B92
| Crystal Structure of the N-terminal domain of human METTL16 in complex with SAH | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | Authors: | Ruszkowska, A, Ruszkowski, M, Dauter, Z, Brown, J.A. | Deposit date: | 2017-10-09 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the RNA methyltransferase domain of METTL16. Sci Rep, 8, 2018
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3BGV
| Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, mRNA cap guanine-N7 methyltransferase | Authors: | Lunin, V.V, Wu, H, Zeng, H, Antoshenko, T, MacKenzie, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Plotnikov, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2007-11-27 | Release date: | 2007-12-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of human RNA (guanine-7-) methyltransferase in complex with SAH. To be Published
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1DN9
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1OIA
| U1A rnp domain 1-95 | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | Authors: | Nagai, K, Evans, P.R. | Deposit date: | 2003-06-12 | Release date: | 2003-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A Nature, 348, 1990
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5UH7
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8JHU
| Legionella effector protein SidI | Descriptor: | Legionella pneumophila effector protein SidI | Authors: | Wang, L, Subramanian, A, Mukherjee, S, Walter, P. | Deposit date: | 2023-05-25 | Release date: | 2023-08-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. Nat.Cell Biol., 25, 2023
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1QAM
| THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM | Descriptor: | ACETATE ION, ERMC' METHYLTRANSFERASE | Authors: | Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C. | Deposit date: | 1999-03-25 | Release date: | 2000-03-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. J.Mol.Biol., 289, 1999
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