3HI9

The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE) binding protein HuR at 2.0 angstrom resolution

Summary for 3HI9

Entry DOI	10.2210/pdb3hi9/pdb
Related	1FXL
Descriptor	ELAV-like protein 1 (2 entities in total)
Functional Keywords	beta1-alpha1-beta2-beta3-alpha2-beta4 topology, methylation, phosphoprotein, rna-binding, transcription
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q15717
Total number of polymer chains	4
Total formula weight	37009.96
Authors	Benoit, R.M.,Kallen, J. (deposition date: 2009-05-19, release date: 2010-03-31, Last modification date: 2023-09-06)
Primary citation	Benoit, R.M.,Meisner, N.C.,Kallen, J.,Graff, P.,Hemmig, R.,Cebe, R.,Ostermeier, C.,Widmer, H.,Auer, M. The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism. J.Mol.Biol., 397:1231-1244, 2010 Cited by PubMed: 20219472 DOI: 10.1016/j.jmb.2010.02.043 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation