3HI9
The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE) binding protein HuR at 2.0 angstrom resolution
Summary for 3HI9
Entry DOI | 10.2210/pdb3hi9/pdb |
Related | 1FXL |
Descriptor | ELAV-like protein 1 (2 entities in total) |
Functional Keywords | beta1-alpha1-beta2-beta3-alpha2-beta4 topology, methylation, phosphoprotein, rna-binding, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q15717 |
Total number of polymer chains | 4 |
Total formula weight | 37009.96 |
Authors | Benoit, R.M.,Kallen, J. (deposition date: 2009-05-19, release date: 2010-03-31, Last modification date: 2023-09-06) |
Primary citation | Benoit, R.M.,Meisner, N.C.,Kallen, J.,Graff, P.,Hemmig, R.,Cebe, R.,Ostermeier, C.,Widmer, H.,Auer, M. The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism. J.Mol.Biol., 397:1231-1244, 2010 Cited by PubMed: 20219472DOI: 10.1016/j.jmb.2010.02.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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