PDB: 13258 resultsInfo pagesStatus searchChemie searchBIRD

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7AXS	Structural characterisation of WDR5:CS-VIP8 interaction in cis state 1 Descriptor: CS-VIP8, (ALQ)(4FO)R(ABA)(DPN)(EDN)(S7Z), WD repeat-containing protein 5 Authors: Werel, L, Essen, L.-O. Deposit date: 2020-11-10 Release date: 2021-12-15 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Bistable Photoswitch Allows in Vivo Control of Hematopoiesis. Acs Cent.Sci., 8, 2022
3M9K	Crystal structure of human thioredoxin C69/73S double-mutant, oxidized form Descriptor: (4S,5S)-1,2-DITHIANE-4,5-DIOL, SULFATE ION, Thioredoxin Authors: Weichsel, A, Montfort, W.R. Deposit date: 2010-03-22 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site. Protein Sci., 19, 2010
6V6V	Crystal structure of oncogenic RhoA mutant G14V complexed with GDP Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Lin, Y, Zheng, Y. Deposit date: 2019-12-06 Release date: 2020-12-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structure of an inactive conformation of GTP-bound RhoA GTPase. Structure, 29, 2021
2FSA	Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state Descriptor: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor Authors: Li, H, Patel, D.J. Deposit date: 2006-01-21 Release date: 2006-07-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
3M9J	Crystal structure of human thioredoxin C69/73S double mutant, reduced form Descriptor: Thioredoxin Authors: Weichsel, A, Montfort, W.R. Deposit date: 2010-03-22 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site. Protein Sci., 19, 2010
3BA5	Crystal structure of D28A mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Blaber, M, Lee, J. Deposit date: 2007-11-07 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3BAQ	Crystal structure of L26A mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Lee, J, Blaber, M. Deposit date: 2007-11-08 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3BA4	Crystal structure of L26D mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Blaber, M, Lee, J. Deposit date: 2007-11-07 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3BAH	Crystal structure of K112N mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1 Authors: Lee, J, Blaber, M. Deposit date: 2007-11-07 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3B9U	Crystal structure of L26N/D28N/H93G mutant of Human acidic fibroblast growth factor Descriptor: Heparin-binding growth factor 1, SULFATE ION Authors: Blaber, M, Lee, J. Deposit date: 2007-11-06 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.55 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3BAV	Crystal structure of L26A/D28N mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Lee, J, Blaber, M. Deposit date: 2007-11-08 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.62 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
3BB2	Crystal structure of L26D/D28N mutant of Human acidic fibroblast growth factor Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Lee, J, Blaber, M. Deposit date: 2007-11-09 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
8IRS	Dopamine Receptor D2R-Gi-Rotigotine complex Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... Authors: Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. Deposit date: 2023-03-19 Release date: 2023-06-07 Last modified: 2023-11-08 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
7AG0	Complex between the bone morphogenetic protein 2 and its antagonist Noggin Descriptor: Bone morphogenetic protein 2, GLYCEROL, Noggin Authors: Robert, C, Bruck, F, Herman, R, Vandevenne, M, Filee, P, Kerff, F, Matagne, A. Deposit date: 2020-09-21 Release date: 2022-04-13 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.104 Å) Cite: Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition. J.Biol.Chem., 299, 2023
7AYZ	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with activator TH10785 Descriptor: N-glycosylase/DNA lyase, NICKEL (II) ION, ~{N}-cyclohexyl-2-cyclopropyl-quinazolin-4-amine Authors: Masuyer, G, Davies, J.R, Stenmark, P. Deposit date: 2020-11-13 Release date: 2022-06-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
7AYY	Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with activator TH10785 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, N-glycosylase/DNA lyase, ... Authors: Masuyer, G, Davies, J.R, Stenmark, P. Deposit date: 2020-11-13 Release date: 2022-06-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
7AZ0	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with TH12161 Descriptor: 2-cyclopropyl-~{N}-(4-iodophenyl)quinazolin-4-amine, N-glycosylase/DNA lyase, NICKEL (II) ION Authors: Davies, J.R, Masuyer, G, Stenmark, P. Deposit date: 2020-11-13 Release date: 2022-06-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
7M05	CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988 Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5 Authors: McMillan, B.J, McKinney, D.C, Timm, D.E. Deposit date: 2021-03-10 Release date: 2021-03-17 Last modified: 2021-08-25 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction. J.Med.Chem., 64, 2021
8FPW	Crystal structure of tumor related RhoA mutant A161V in complex with GDP Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Lin, Y, Zheng, Y. Deposit date: 2023-01-05 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Tumor related RhoA mutants interact with effectors in the GDP-bound state To Be Published
8FPX	Crystal structure of tumor related RhoA mutant A161P in complex with GDP Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Lin, Y, Zheng, Y. Deposit date: 2023-01-05 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Tumor related RhoA mutants interact with effectors in the GDP-bound state To Be Published
7BED	X-ray structure of WDR5 bound to the WDR5 win motif peptide Descriptor: SULFATE ION, WD repeat-containing protein 5 Authors: McVey, C.E, Kaye, K.M. Deposit date: 2020-12-23 Release date: 2021-12-08 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.26 Å) Cite: MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
7BCY	X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide Descriptor: ORF 73, WD repeat-containing protein 5 Authors: McVey, C.E, Kaye, K.M. Deposit date: 2020-12-21 Release date: 2021-12-08 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res., 49, 2021
3CQA	Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. Deposit date: 2008-04-02 Release date: 2009-04-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1. Acta Crystallogr.,Sect.F, 65, 2009
3CRI	Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION Authors: Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. Deposit date: 2008-04-07 Release date: 2009-02-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1. Acta Crystallogr.,Sect.F, 65, 2009
3CRH	Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala Descriptor: Heparin-binding growth factor 1, SULFATE ION Authors: Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. Deposit date: 2008-04-07 Release date: 2009-02-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1. Acta Crystallogr.,Sect.F, 65, 2009

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