7AG0
Complex between the bone morphogenetic protein 2 and its antagonist Noggin
Summary for 7AG0
| Entry DOI | 10.2210/pdb7ag0/pdb |
| Descriptor | Noggin, Bone morphogenetic protein 2, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | bmp-2, tgf-beta superfamily, cysteine-knot, cytokine |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 36505.08 |
| Authors | Robert, C.,Bruck, F.,Herman, R.,Vandevenne, M.,Filee, P.,Kerff, F.,Matagne, A. (deposition date: 2020-09-21, release date: 2022-04-13, Last modification date: 2024-02-07) |
| Primary citation | Robert, C.,Kerff, F.,Bouillenne, F.,Gavage, M.,Vandevenne, M.,Filee, P.,Matagne, A. Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition. J.Biol.Chem., 299:102892-102892, 2023 Cited by PubMed: 36642181DOI: 10.1016/j.jbc.2023.102892 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.104 Å) |
Structure validation
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