3CRI

Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala

Summary for 3CRI

• Entry DOI: 10.2210/pdb3cri/pdb
• Related: 3CRG 3CRH
• Descriptor: Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: crystal packing, acetylation, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, hormone
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: P05230
• Total number of polymer chains: 2
• Total formula weight: 33427.38

Authors

Meher, A.K.,Honjo, E.,Kuroki, R.,Lee, J.,Somasundaram, T.,Blaber, M. (deposition date: 2008-04-07, release date: 2009-02-17, Last modification date: 2024-02-21)

• Primary citation: Meher, A.K.,Blaber, S.I.,Lee, J.,Honjo, E.,Kuroki, R.,Blaber, M.; Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.; Acta Crystallogr.,Sect.F, 65:1136-1140, 2009; PubMed: 19923735; DOI: 10.1107/S1744309109036987

Experimental method

X-RAY DIFFRACTION (2.1 Å)