6V6V

Crystal structure of oncogenic RhoA mutant G14V complexed with GDP

Summary for 6V6V

• Entry DOI: 10.2210/pdb6v6v/pdb
• Related: 6V6M 6V6U
• Descriptor: Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: gtpase, switch i, switch ii, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 21264.31

Authors

Lin, Y.,Zheng, Y. (deposition date: 2019-12-06, release date: 2020-12-23, Last modification date: 2023-10-11)

• Primary citation: Lin, Y.,Lu, S.,Zhang, J.,Zheng, Y.; Structure of an inactive conformation of GTP-bound RhoA GTPase.; Structure, 29:553-563.e5, 2021; PubMed: 33497604; DOI: 10.1016/j.str.2020.12.015

Experimental method

X-RAY DIFFRACTION (1.4 Å)