PDB: 10140 resultsInfo pagesStatus searchChemie searchBIRD

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8R9X	Local refinement of the PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Debski-Antoniak, O, Hurdiss, D.L. Deposit date: 2023-11-30 Release date: 2024-06-05 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein. Nat Commun, 15, 2024
7LRT	Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 spike glycoprotein, ... Authors: Zhou, T, Tsybovsky, T. Deposit date: 2021-02-17 Release date: 2021-07-14 Last modified: 2021-08-25 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
8TW3	hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ... Authors: Rush, S.A, McLellan, J.S. Deposit date: 2023-08-19 Release date: 2024-01-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein. Mbio, 15, 2024
7KBK	Ricin bound to VHH antibody V6E11 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... Authors: Rudolph, M.J. Deposit date: 2020-10-02 Release date: 2021-08-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.091 Å) Cite: Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface. J.Mol.Biol., 433, 2021
7KBI	Ricin bound to VHH antibody V5E1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ricin chain A, ... Authors: Rudolph, M.J. Deposit date: 2020-10-02 Release date: 2021-08-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.049 Å) Cite: Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface. J.Mol.Biol., 433, 2021
6W7S	Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 2G10 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G10 (Fab heavy chain), 2G10 (Fab light chain), ... Authors: Cogan, D.P, Mathews, I.I, Khosla, C. Deposit date: 2020-03-19 Release date: 2020-09-09 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction. J.Am.Chem.Soc., 142, 2020
7MDT	BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... Authors: Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. Deposit date: 2021-04-06 Release date: 2022-01-26 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
6WH9	Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 1D10 Descriptor: 1D10 (Fab heavy chain), 1D10 (Fab light chain), KR1, ... Authors: Cogan, D.P, Mathews, I.I, Khosla, C. Deposit date: 2020-04-07 Release date: 2020-09-09 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction. J.Am.Chem.Soc., 142, 2020
7KDU	Ricin bound to VHH antibody V5E4 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ricin chain A, ... Authors: Rudolph, M.J. Deposit date: 2020-10-09 Release date: 2021-08-04 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.809 Å) Cite: Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface. J.Mol.Biol., 433, 2021
8SDF	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.4 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yuan, M, Wilson, I.A. Deposit date: 2023-04-06 Release date: 2024-03-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv, 2023
8SDG	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.43 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralizing antibody CC25.43 heavy chain, Neutralizing antibody CC25.43 light chain, ... Authors: Yuan, M, Wilson, I.A. Deposit date: 2023-04-06 Release date: 2024-03-13 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv, 2023
8SDH	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.56 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralizing antibody CC25.56 Heavy Chain, ... Authors: Yuan, M, Wilson, I.A. Deposit date: 2023-04-06 Release date: 2024-08-07 Last modified: 2024-09-11 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv, 2023
5AWN	Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab Descriptor: Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab Authors: Lee, J.H, Wilson, I.A, Ward, A.B. Deposit date: 2015-07-06 Release date: 2015-11-11 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.887 Å) Cite: Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun, 6, 2015
7FCQ	Crystallographic structure of neutralizing antibody P14-44 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, P14-44 antibody Fab fragment heavy chain, ... Authors: Zheng, P, Jin, T. Deposit date: 2021-07-15 Release date: 2022-06-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance. J.Clin.Invest., 132, 2022
7TCQ	Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide Descriptor: Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, DI(HYDROXYETHYL)ETHER, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-12-28 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability. Structure, 30, 2022
7LRS	Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain Descriptor: Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, antibody A23-58.1 heavy chain, ... Authors: Zhou, T, Tsybovsky, Y. Deposit date: 2021-02-17 Release date: 2021-07-14 Last modified: 2021-08-25 Method: ELECTRON MICROSCOPY (3.89 Å) Cite: Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
8U5L	MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK virus VP1 Descriptor: Capsid protein VP1, scFv fragment of the monoclonal antibody MAU868 Authors: Knapp, M.S, Ornelas, E. Deposit date: 2023-09-12 Release date: 2024-08-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Nonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1. Am J Transplant, 2024
5NB5	Principles for computational design of antibodies Descriptor: design of antibodies Authors: Dym, O, Fleishman, S.J. Deposit date: 2017-03-01 Release date: 2017-09-27 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Principles for computational design of binding antibodies. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NBI	Principles for computational design of antibodies Descriptor: Design of antibodies Authors: Dym, O, Fleishman, S.J. Deposit date: 2017-03-02 Release date: 2017-09-27 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Principles for computational design of binding antibodies. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7N4I	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057. Descriptor: GLYCEROL, Spike protein S1, WRAIR-2057 Antibody Fab Heavy Chain, ... Authors: Sankhala, R.S, Joyce, M.G. Deposit date: 2021-06-04 Release date: 2021-10-06 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.284 Å) Cite: Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations. Nat.Immunol., 22, 2021
7N4J	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2173. Descriptor: Spike protein S1, WRAIR-2173 antibody Fab heavy chain, WRAIR-2173 antibody Fab light chain, ... Authors: Sankhala, R.S, Joyce, M.G. Deposit date: 2021-06-04 Release date: 2021-10-06 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.207 Å) Cite: Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations. Nat.Immunol., 22, 2021
7DEU	Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv Authors: Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y. Deposit date: 2020-11-05 Release date: 2021-03-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
7DEO	Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... Authors: Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. Deposit date: 2020-11-04 Release date: 2021-03-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
7DET	Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv Authors: Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. Deposit date: 2020-11-05 Release date: 2021-03-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
6NF2	Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 Descriptor: 0PV-c.01 Heavy Chain, 0PV-c.01 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2018-12-18 Release date: 2019-07-24 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

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