6W7S
Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 2G10
Summary for 6W7S
Entry DOI | 10.2210/pdb6w7s/pdb |
Descriptor | EryAI, 2G10 (Fab heavy chain), 2G10 (Fab light chain), ... (6 entities in total) |
Functional Keywords | ketoreductase, antibody fragment, oxidoreductase-immune system complex, oxidoreductase/immune system |
Biological source | Saccharopolyspora erythraea More |
Total number of polymer chains | 3 |
Total formula weight | 103532.37 |
Authors | Cogan, D.P.,Mathews, I.I.,Khosla, C. (deposition date: 2020-03-19, release date: 2020-09-09, Last modification date: 2023-10-18) |
Primary citation | Cogan, D.P.,Li, X.,Sevillano, N.,Mathews, I.I.,Matsui, T.,Craik, C.S.,Khosla, C. Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction. J.Am.Chem.Soc., 142:14933-14939, 2020 Cited by PubMed: 32786753DOI: 10.1021/jacs.0c05133 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report