6W7S
Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 2G10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EryAI | polymer | 485 | 50889.0 | 1 | UniProt (Q5UNP6) UniProt (by SIFTS) (Q03131) | Saccharopolyspora erythraea | |
| 2 | B (H) | 2G10 (Fab heavy chain) | polymer | 255 | 27107.5 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | 2G10 (Fab light chain) | polymer | 236 | 25305.2 | 1 | Homo sapiens (Human) | ||
| 4 | D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | E (L) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G, H (A, H, L) | water | water | 18.0 | 419 | Chemie (HOH) |
Sequence modifications
A: 1448 - 1928 (UniProt: Q5UNP6)
| PDB | External Database | Details |
|---|---|---|
| Gly 1444 | - | expression tag |
| Ser 1445 | - | expression tag |
| His 1446 | - | expression tag |
| Met 1447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 103301.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 230.7 | |
| All* | Total formula weight | 103532.4 |
