PDB: 11971 resultsInfo pagesStatus searchChemie searchBIRD

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4UP0	Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide Descriptor: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... Authors: Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. Deposit date: 2014-06-11 Release date: 2014-11-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9, 2014
1H3I	Crystal structure of the Histone Methyltransferase SET7/9 Descriptor: HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE, MAGNESIUM ION Authors: Wilson, J.R, Jing, C, Walker, P.A, Martin, S.R, Howell, S.A, Blackburn, G.M, Gamblin, S.J, Xiao, B. Deposit date: 2002-09-04 Release date: 2002-11-11 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9 Cell(Cambridge,Mass.), 111, 2002
2YFW	Heterotetramer structure of Kluyveromyces lactis Cse4,H4 Descriptor: HISTONE H3-LIKE CENTROMERIC PROTEIN CSE4, HISTONE H4 Authors: Cho, U.S, Harrison, S.C. Deposit date: 2011-04-08 Release date: 2011-05-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Recognition of the Centromere-Specific Histone Cse4 by the Chaperone Scm3. Proc.Natl.Acad.Sci.USA, 108, 2011
1CT6	SOLUTION STRUCTURE OF CGGIRGERG IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 11 STRUCTURES Descriptor: HISTONE H3 PEPTIDE Authors: Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, M.T. Deposit date: 1999-08-19 Release date: 1999-09-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
2R10	Structure of an acetylated Rsc4 tandem bromodomain Histone Chimera Descriptor: 1,2-ETHANEDIOL, Chromatin structure-remodeling complex protein RSC4, LINKER, ... Authors: VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. Deposit date: 2007-08-21 Release date: 2007-10-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol.Cell, 27, 2007
8OWT	SARS-CoV-2 spike RBD with A8 and H3 nanobodies bound Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody A8, ... Authors: Mikolajek, H, Naismith, J.H, Owens, R.J. Deposit date: 2023-04-28 Release date: 2024-05-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2. Open Biology, 14, 2024
1CS9	SOLUTION STRUCTURE OF CGGIRGERA IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 7 STRUCTURES Descriptor: HISTONE H3 PEPTIDE Authors: Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, M.T. Deposit date: 1999-08-18 Release date: 1999-09-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
3MO2	human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E67 Descriptor: 7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... Authors: Chang, Y, Horton, J.R, Cheng, X. Deposit date: 2010-04-22 Release date: 2010-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
3MO5	Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E72 Descriptor: 7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... Authors: Chang, Y, Horton, J.R, Cheng, X. Deposit date: 2010-04-22 Release date: 2010-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
6A5M	Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 2 Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... Authors: Li, X, Du, J. Deposit date: 2018-06-24 Release date: 2018-08-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.301 Å) Cite: Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8I3F	Crystal structure of Rco1-Eaf3 with peptide of histone H3 N-terminal Descriptor: Chromatin modification-related protein EAF3, Histone H3, RCO1 isoform 1, ... Authors: Chen, Z, Xu, C. Deposit date: 2023-01-17 Release date: 2023-05-31 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4. Cell Discov, 9, 2023
6A5N	Crystal structure of Arabidopsis thaliana SUVH6 in complex with methylated DNA Descriptor: DNA (5'-D(*CP*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, ... Authors: Li, X, Du, J. Deposit date: 2018-06-24 Release date: 2018-08-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6A5K	Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1 Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... Authors: Li, X, Du, J. Deposit date: 2018-06-24 Release date: 2018-08-29 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4IUT	crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... Authors: Du, J, Patel, D.J. Deposit date: 2013-01-21 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
4IUU	Crystal structure of SHH1 SAWADEE domain in complex with H3K9me1 peptide Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... Authors: Du, J, Patel, D.J. Deposit date: 2013-01-21 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
4IUR	crystal structure of SHH1 SAWADEE domain in complex with H3K9me3 peptide Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ... Authors: Patel, D.J, Du, J. Deposit date: 2013-01-21 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.501 Å) Cite: Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature, 498, 2013
5YYF	Crystal structure of AF9 YEATS domain in complex with a peptide inhibitor "PHQ-H3(Q5-K9)" modified at K9 with 2-furancarboyl group Descriptor: 2-FUROIC ACID, Peptide inhibitor PHQ-H3(Q5-K9), Protein AF-9, ... Authors: Li, Y, Li, H. Deposit date: 2017-12-09 Release date: 2018-11-07 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.903 Å) Cite: Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking. Nat. Chem. Biol., 14, 2018
7D69	Cryo-EM structure of the nucleosome containing Giardia histones Descriptor: 601L DNA (145-MER), Histone H2A, Histone H2B, ... Authors: Sato, S, Takizawa, Y, Kurumizaka, H. Deposit date: 2020-09-29 Release date: 2021-09-08 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones. Nucleic Acids Res., 49, 2021
3MO0	Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E11 Descriptor: 1,2-ETHANEDIOL, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... Authors: Chang, Y, Horton, J.R, Cheng, X. Deposit date: 2010-04-22 Release date: 2010-06-30 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
2LTC	Fas1-4, R555W Descriptor: Transforming growth factor-beta-induced protein ig-h3 Authors: Underhaug, J, Nielsen, N, Runager, K. Deposit date: 2012-05-16 Release date: 2013-08-21 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization. Biochim.Biophys.Acta, 1834, 2013
3SOW	Structure of UHRF1 PHD finger in complex with histone H3K4me3 1-9 peptide Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION Authors: Rajakumara, E, Patel, D.J. Deposit date: 2011-06-30 Release date: 2011-08-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9501 Å) Cite: PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol.Cell, 43, 2011
4NM8	Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ... Authors: Lee, P.S, Wilson, I.A. Deposit date: 2013-11-14 Release date: 2013-12-25 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (4.0041 Å) Cite: A common solution to group 2 influenza virus neutralization. Proc.Natl.Acad.Sci.USA, 111, 2014
6BUZ	Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ... Authors: Chittori, S, Hong, J, Kelly, A.E, Bai, Y, Subramaniam, S. Deposit date: 2017-12-11 Release date: 2017-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.92 Å) Cite: Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N. Science, 359, 2018
6C0W	Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A Descriptor: 147 mer DNA, Centromere protein N, Histone H2A, ... Authors: Zhou, K, Pentakota, S, Vetter, I.R, Morgan, G.P, Petrovic, A, Musacchio, A, Luger, K. Deposit date: 2018-01-02 Release date: 2018-01-17 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Decoding the centromeric nucleosome through CENP-N. Elife, 6, 2017
2YFV	The heterotrimeric complex of Kluyveromyces lactis Scm3, Cse4 and H4 Descriptor: HISTONE H3-LIKE CENTROMERIC PROTEIN CSE4, HISTONE H4, IODIDE ION, ... Authors: Cho, U.S, Harrison, S.C. Deposit date: 2011-04-08 Release date: 2011-05-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Recognition of the Centromere-Specific Histone Cse4 by the Chaperone Scm3. Proc.Natl.Acad.Sci.USA, 108, 2011

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