6BUZ

Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N

Summary for 6BUZ

• Entry DOI: 10.2210/pdb6buz/pdb
• EMDB information: 7293
• Descriptor: Histone H3-like centromeric protein A, Histone H4, Histone H2A, ... (7 entities in total)
• Functional Keywords: structural protein-dna complex, histone fold, centromeric nucleosome, kinetochore, structural protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 11
• Total formula weight: 281737.05

Authors

Chittori, S.,Hong, J.,Kelly, A.E.,Bai, Y.,Subramaniam, S. (deposition date: 2017-12-11, release date: 2017-12-20, Last modification date: 2024-03-13)

• Primary citation: Chittori, S.,Hong, J.,Saunders, H.,Feng, H.,Ghirlando, R.,Kelly, A.E.,Bai, Y.,Subramaniam, S.; Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N.; Science, 359:339-343, 2018; PubMed: 29269420; DOI: 10.1126/science.aar2781

Experimental method

ELECTRON MICROSCOPY (3.92 Å)