7LI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7li4 by Molmil](/molmil-images/mine/7li4) | Structure of LRRK2 after symmetry expansion | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 | Authors: | Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. | Deposit date: | 2021-01-26 | Release date: | 2021-06-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural analysis of the full-length human LRRK2. Cell, 184, 2021
|
|
1GNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gnu by Molmil](/molmil-images/mine/1gnu) | GABA(A) receptor associated protein GABARAP | Descriptor: | GABARAP, NICKEL (II) ION | Authors: | Knight, D, Harris, R, Moss, S, Driscoll, P.C, Keep, N.H. | Deposit date: | 2001-10-09 | Release date: | 2001-12-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The X-Ray Crystal Structure and Putative Ligand-Derived Peptide Binding Properties of Gamma-Aminobutyric Acid Receptor Type a Receptor-Associated Protein J.Biol.Chem., 277, 2002
|
|
4K17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k17 by Molmil](/molmil-images/mine/4k17) | Crystal Structure of mouse CARMIL residues 1-668 | Descriptor: | CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, Leucine-rich repeat-containing protein 16A, ... | Authors: | Zwolak, A, Dominguez, R. | Deposit date: | 2013-04-04 | Release date: | 2013-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.895 Å) | Cite: | CARMIL leading edge localization depends on a non-canonical PH domain and dimerization. Nat Commun, 4, 2013
|
|
4KUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kuj by Molmil](/molmil-images/mine/4kuj) | Structural and functional characterization of a novel Alpha Kinase from Entamoeba histolytica | Descriptor: | DI(HYDROXYETHYL)ETHER, Protein kinase, putative, ... | Authors: | Rehman, S.A.A, Tarique, K.F, Bhattacharya, A, Gourinath, S, Mansuri, M.S. | Deposit date: | 2013-05-22 | Release date: | 2014-05-28 | Last modified: | 2020-12-02 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural and functional characterization of a novel Alpha Kinase from Entamoeba histolytica To be Published
|
|
4L2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l2w by Molmil](/molmil-images/mine/4l2w) | |
4KAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kax by Molmil](/molmil-images/mine/4kax) | Crystal structure of the Grp1 PH domain in complex with Arf6-GTP | Descriptor: | ADP-ribosylation factor 6, CITRIC ACID, Cytohesin-3, ... | Authors: | Lambright, D.G, Malaby, A.W, van den Berg, B. | Deposit date: | 2013-04-23 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
5O2Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o2z by Molmil](/molmil-images/mine/5o2z) | Domain swap dimer of the G167R variant of gelsolin second domain | Descriptor: | ACETATE ION, CALCIUM ION, CITRATE ANION, ... | Authors: | Boni, F, Milani, M, Mastrangelo, E, de Rosa, M. | Deposit date: | 2017-05-23 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein. Hum. Mol. Genet., 27, 2018
|
|
4K95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k95 by Molmil](/molmil-images/mine/4k95) | Crystal Structure of Parkin | Descriptor: | E3 ubiquitin-protein ligase parkin, ZINC ION | Authors: | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (6.499 Å) | Cite: | Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
|
|
4NL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nl0 by Molmil](/molmil-images/mine/4nl0) | Structural and functional characterization of a novel Alpha Kinase in complex with ADP from Entamoeba histolytica | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Protein kinase, putative, ... | Authors: | Tarique, K.F, Rehman, S.A.A, Bhattacharya, A, Gourinath, S, Mansuri, M.S. | Deposit date: | 2013-11-13 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural and functional characterization of a novel Alpha Kinase in complex with ADP from Entamoeba histolytica To be Published
|
|
2J1L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j1l by Molmil](/molmil-images/mine/2j1l) | Crystal Structure of Human Rho-related GTP-binding protein RhoD | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RHO-RELATED GTP-BINDING PROTEIN RHOD | Authors: | Pike, A.C.W, Johansson, C, Gileadi, C, Niesen, F.H, Sobott, F, Schoch, G, Elkins, J, Smee, C, Gorrec, F, Watt, S, Bray, J, Turnbull, A.P, von Delft, F, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D. | Deposit date: | 2006-08-14 | Release date: | 2006-09-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod To be Published
|
|
4ZQ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zq0 by Molmil](/molmil-images/mine/4zq0) | |
8TH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8th8 by Molmil](/molmil-images/mine/8th8) | |
8TID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tid by Molmil](/molmil-images/mine/8tid) | Combined linker domain of N-DRC and associated proteins Tetrahymena | Descriptor: | AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ... | Authors: | Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H. | Deposit date: | 2023-07-19 | Release date: | 2023-09-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
|
|
8G7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g7u by Molmil](/molmil-images/mine/8g7u) | |
8G7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g7t by Molmil](/molmil-images/mine/8g7t) | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end) | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
|
|
8G7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g7v by Molmil](/molmil-images/mine/8g7v) | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2023-02-17 | Release date: | 2023-11-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
|
|
2JXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jxb by Molmil](/molmil-images/mine/2jxb) | Structure of CD3epsilon-Nck2 first SH3 domain complex | Descriptor: | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 | Authors: | Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G. | Deposit date: | 2007-11-09 | Release date: | 2008-09-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity. J.Mol.Biol., 380, 2008
|
|
2JS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2js2 by Molmil](/molmil-images/mine/2js2) | |
8T71
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t71 by Molmil](/molmil-images/mine/8t71) | Crystal Structure of WT KRAS4a with bound GDP and Mg ion | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K. | Deposit date: | 2023-06-19 | Release date: | 2024-02-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties. Sci Adv, 10, 2024
|
|
8T72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t72 by Molmil](/molmil-images/mine/8t72) | Crystal structure of WT KRAS4a with bound GMPPNP and Mg ion | Descriptor: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K. | Deposit date: | 2023-06-19 | Release date: | 2024-02-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties. Sci Adv, 10, 2024
|
|
8T75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t75 by Molmil](/molmil-images/mine/8t75) | |
8T74
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t74 by Molmil](/molmil-images/mine/8t74) | |
8TI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ti6 by Molmil](/molmil-images/mine/8ti6) | Crystal structure of Tyr p 36.0101 | Descriptor: | Profilin, Proline-rich peptide, SULFATE ION | Authors: | O'Malley, A, Sankaran, S, Chruszcz, M. | Deposit date: | 2023-07-19 | Release date: | 2024-05-08 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity. Biol.Chem., 405, 2024
|
|
8TI7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ti7 by Molmil](/molmil-images/mine/8ti7) | |
8TI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ti5 by Molmil](/molmil-images/mine/8ti5) | Crystal structure of Tyr p 36.0101 | Descriptor: | Profilin, SULFATE ION | Authors: | O'Malley, A, Sankaran, S, Chruszcz, M. | Deposit date: | 2023-07-19 | Release date: | 2024-05-08 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity. Biol.Chem., 405, 2024
|
|