4KAX

Crystal structure of the Grp1 PH domain in complex with Arf6-GTP

Summary for 4KAX

• Entry DOI: 10.2210/pdb4kax/pdb
• Descriptor: ADP-ribosylation factor 6, Cytohesin-3, GUANOSINE-5'-TRIPHOSPHATE, ... (9 entities in total)
• Functional Keywords: ph domain, phosphoinositides, protein binding-signaling protein complex, protein binding/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytosol : P62330 O43739
• Total number of polymer chains: 2
• Total formula weight: 40216.08

Authors

Lambright, D.G.,Malaby, A.W.,van den Berg, B. (deposition date: 2013-04-23, release date: 2013-08-14, Last modification date: 2024-02-28)

• Primary citation: Malaby, A.W.,van den Berg, B.,Lambright, D.G.; Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors.; Proc.Natl.Acad.Sci.USA, 110:14213-14218, 2013; PubMed: 23940353; DOI: 10.1073/pnas.1301883110

Experimental method

X-RAY DIFFRACTION (1.85 Å)