4L2W

Crystal structure of the Shroom-Binding domain of human Rock1

Summary for 4L2W

Entry DOI	10.2210/pdb4l2w/pdb
Descriptor	Rho-associated protein kinase 1 (2 entities in total)
Functional Keywords	coiled-coil, shroom sd2, kinase, myosin, protein binding
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q13464
Total number of polymer chains	4
Total formula weight	40304.37
Authors	Mohan, S.,VanDemark, A.P. (deposition date: 2013-06-04, release date: 2014-04-16, Last modification date: 2024-02-28)
Primary citation	Mohan, S.,Das, D.,Bauer, R.J.,Heroux, A.,Zalewski, J.K.,Heber, S.,Dosunmu-Ogunbi, A.M.,Trakselis, M.A.,Hildebrand, J.D.,Vandemark, A.P. Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. Plos One, 8:e81075-e81075, 2013 Cited by PubMed: 24349032 DOI: 10.1371/journal.pone.0081075 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.49 Å)

Structure validation