PDB: 45331 resultsInfo pagesStatus searchChemie searchBIRD

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3SYO	Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION Authors: Whorton, M.R, MacKinnon, R. Deposit date: 2011-07-18 Release date: 2011-10-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.54 Å) Cite: Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147, 2011
1GVD	CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT Descriptor: AMMONIUM ION, MYB PROTO-ONCOGENE PROTEIN, SULFATE ION Authors: Tahirov, T.H, Ogata, K. Deposit date: 2002-02-08 Release date: 2003-07-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of C-Myb DNA-Binding Domain: Specific Na+ Binding and Correlation with NMR Structure To be Published
3GIS	Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin Descriptor: CALCIUM ION, Prothrombin, SULFATE ION, ... Authors: Adams, T.E, Huntington, J.A. Deposit date: 2009-03-06 Release date: 2009-08-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Molecular basis of thrombomodulin activation of slow thrombin J.Thromb.Haemost., 7, 2009
4QE7	Open MthK pore structure soaked in 10 mM Ba2+/100 mM Na+ Descriptor: BARIUM ION, Calcium-gated potassium channel MthK Authors: Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S. Deposit date: 2014-05-15 Release date: 2014-07-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Ionic interactions of Ba2+ blockades in the MthK K+ channel J.Gen.Physiol., 144, 2014
4P4K	Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity and auto immunity Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM, HLA class II histocompatibility antigen, ... Authors: Clayton, G.M, Crawford, F, Kappler, J.W. Deposit date: 2014-03-12 Release date: 2014-07-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
2YXT	Human Pyridoxal Kinase Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Pyridoxal kinase, ... Authors: Safo, M.K, Musayev, F.N, Ko, T.P, Schirch, V. Deposit date: 2007-04-27 Release date: 2008-03-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. Protein Sci., 16, 2007
2YXU	Human Pyridoxal Kinase Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Safo, M.K, Musayev, F.N, Ko, T.P, Schirch, V. Deposit date: 2007-04-27 Release date: 2008-03-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. Protein Sci., 16, 2007
7T84	Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32 G26D T57I variant Descriptor: CITRIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Nemeth, G.R, Skiba, M.A, Kruse, A.C. Deposit date: 2021-12-15 Release date: 2022-12-07 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.6 Å) Cite: An in silico method to assess antibody fragment polyreactivity. Nat Commun, 13, 2022
8FHD	Cryo-EM structure of human voltage-gated sodium channel Nav1.6 Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (5E,17R,20S)-23-amino-20-hydroxy-14,20-dioxo-15,19,21-trioxa-20lambda~5~-phosphatricos-5-en-17-yl hexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... Authors: Fan, X, Huang, J, Yan, N. Deposit date: 2022-12-14 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cryo-EM structure of human voltage-gated sodium channel Na v 1.6. Proc.Natl.Acad.Sci.USA, 120, 2023
8FV6	E coli. CTP synthase in complex with dF-dCTP Descriptor: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID, ... Authors: Holyoak, T, McLeod, M.J, Tran, N. Deposit date: 2023-01-18 Release date: 2023-05-24 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.25 Å) Cite: A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FV8	E coli. CTP synthase in complex with dF-dCTP + ADP Descriptor: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-DIPHOSPHATE, CTP synthase, ... Authors: Holyoak, T, McLeod, M.J, Tran, N. Deposit date: 2023-01-18 Release date: 2023-05-24 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.05 Å) Cite: A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVA	E coli. CTP synthase in complex with F-araCTP Descriptor: 4-amino-1-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CTP synthase, MALONIC ACID, ... Authors: Holyoak, T, McLeod, M.J, Tran, N. Deposit date: 2023-01-18 Release date: 2023-05-24 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FV7	E coli. CTP synthase in complex with dF-dCTP + ATP Descriptor: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, ... Authors: Holyoak, T, McLeod, M.J, Tran, N. Deposit date: 2023-01-18 Release date: 2023-05-24 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.08 Å) Cite: A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
3AGW	Crystal Structure of the Cytoplasmic Domain of G-Protein-Gated Inward Rectifier Potassium Channel Kir3.2 in the absence of Na+ Descriptor: ETHANOL, G protein-activated inward rectifier potassium channel 2, MAGNESIUM ION Authors: Inanobe, A. Deposit date: 2010-04-08 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A structural determinant for the control of PIP2 sensitivity in G protein-gated inward rectifier K+ channels J.Biol.Chem., 285, 2010
8JZS	Outward-facing SLC15A4 dimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter Authors: Zhang, S.S, Chen, X.D, Xie, M. Deposit date: 2023-07-06 Release date: 2023-09-27 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
8JZU	SLC15A4_TASL complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein Authors: Zhang, S.S, Chen, X.D, Xie, M. Deposit date: 2023-07-06 Release date: 2023-09-27 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
8JZR	Outward_facing SLC15A4 monomer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, lysosomal transporter,ALFA tag Authors: Zhang, S.S, Chen, X.D, Xie, M. Deposit date: 2023-07-06 Release date: 2023-09-27 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
8K69	Cryo-EM structure of Oryza sativa HKT2;2/1 at 2.3 angstrom Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... Authors: Wang, X, Shen, X, Qu, Y, Wang, C, Shen, H. Deposit date: 2023-07-25 Release date: 2024-04-03 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.33 Å) Cite: Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters. Nat.Plants, 10, 2024
8K66	Cryo-EM structure of Oryza sativa HKT2;1 at 2.5 angstrom Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... Authors: Wang, X, Shen, X, Qu, Y, Wang, C, Shen, H. Deposit date: 2023-07-25 Release date: 2024-04-03 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters. Nat.Plants, 10, 2024
7S0V	The role of an Asp-Asp pair in the structure, function and inhibition of CTX-M Class A Beta-lactamase Descriptor: 3-(1H-pyrazol-1-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide, Beta-lactamase Authors: Kemp, M.T, Chen, Y. Deposit date: 2021-08-31 Release date: 2021-11-10 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Class A beta-lactamase. Febs Lett., 595, 2021
5YCX	X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis with c-terminal His tag (Apo form) Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Authors: Kim, H.T. Deposit date: 2017-09-08 Release date: 2018-02-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.701 Å) Cite: Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis Biochem. Biophys. Res. Commun., 493, 2017
5YCV	X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis (Apo form) Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Authors: Kim, H.T. Deposit date: 2017-09-08 Release date: 2018-02-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.851 Å) Cite: Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis Biochem. Biophys. Res. Commun., 493, 2017
5YSO	Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434 Descriptor: 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma Authors: Cho, S.J, Chin, J.W, Yoon, H.S, Jeon, Y.H, Bae, J.H, Song, J.Y. Deposit date: 2017-11-14 Release date: 2018-12-26 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.501 Å) Cite: A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERR gamma ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer. Clin.Cancer Res., 25, 2019
6K25	Crystal structure of Ca-unbound human Annexin A5 in low salt condition Descriptor: Annexin A5 Authors: Hong, S, Ha, N.-C. Deposit date: 2019-05-13 Release date: 2020-03-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.401 Å) Cite: High-resolution structures of annexin A5 in a two-dimensional array. J.Struct.Biol., 209, 2020
1GWD	Tri-iodide derivative of hen egg-white lysozyme Descriptor: 1,2-ETHANEDIOL, CARBON MONOXIDE, CHLORIDE ION, ... Authors: Evans, G, Bricogne, G. Deposit date: 2002-03-14 Release date: 2002-06-06 Last modified: 2017-06-28 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment Acta Crystallogr.,Sect.D, 58, 2002

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