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2ZP3
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BU of 2zp3 by Molmil
Carboxylic ester hydrolase, single mutant d49n of bovine pancreatic pla2 enzyme
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Kanaujia, S.P, Sekar, K.
Deposit date:2008-06-27
Release date:2008-11-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures and molecular-dynamics studies of three active-site mutants of bovine pancreatic phospholipase A(2)
Acta Crystallogr.,Sect.D, 64, 2008
3BJW
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BU of 3bjw by Molmil
Crystal Structure of ecarpholin S complexed with suramin
Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Phospholipase A2
Authors:Zhou, X, Sivaraman, J.
Deposit date:2007-12-04
Release date:2007-12-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom
Biophys.J., 95, 2008
8ZYM
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BU of 8zym by Molmil
Complex structure of 60 Fab bound to DS2 prefusion F trimer
Descriptor: Fusion glycoprotein F0,Expression tag, antibody light chain, antidody heavy chain
Authors:Wang, X, Ge, J, Guo, F.
Deposit date:2024-06-18
Release date:2025-04-30
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection.
Npj Vaccines, 9, 2024
3HZW
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BU of 3hzw by Molmil
Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB)
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
Authors:Fernandes, C.A.H, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-24
Release date:2010-05-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I03
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BU of 3i03 by Molmil
Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
Authors:Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-24
Release date:2010-05-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
5LP1
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BU of 5lp1 by Molmil
CRYSTAL STRUCTURE OF HUMAN LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 IN COMPLEX WITH A [1.1.1]BICYCLOPENTANE-CONTAINING INHIBITOR AT 1.91A RESOLUTION.
Descriptor: CHLORIDE ION, Platelet-activating factor acetylhydrolase, ~{N}-[2-(diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-4-oxidanylidene-5~{H}-cyclopenta[d]pyrimidin-1-yl]-~{N}-[[3-[4-(trifluoromethyl)phenyl]-1-bicyclo[1.1.1]pentanyl]methyl]ethanamide
Authors:Somers, D.
Deposit date:2016-08-11
Release date:2017-02-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor.
ACS Med Chem Lett, 8, 2017
1Q6V
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BU of 1q6v by Molmil
First crystal structure of a C49 monomer PLA2 from the venom of Daboia russelli pulchella at 1.8 A resolution
Descriptor: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Pal, A, Jabeen, T, Sharma, S, Singh, T.P.
Deposit date:2003-08-14
Release date:2004-05-04
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:First crystal structure of a C49 PLA2 from the venom of Daboia russelli pulchella at 1.8A resolution
To be Published
5K6F
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BU of 5k6f by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant.
Descriptor: Fusion glycoprotein F0
Authors:Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
Deposit date:2016-05-24
Release date:2016-08-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
3DDQ
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BU of 3ddq by Molmil
Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor roscovitine
Descriptor: Cell division protein kinase 2, Cyclin-A2, MONOTHIOGLYCEROL, ...
Authors:Echalier, A, Endicott, J.A.
Deposit date:2008-06-06
Release date:2008-07-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases.
Oncogene, 27, 2008
4NTW
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BU of 4ntw by Molmil
Structure of acid-sensing ion channel in complex with snake toxin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
4NTY
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BU of 4nty by Molmil
Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
4NTX
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BU of 4ntx by Molmil
Structure of acid-sensing ion channel in complex with snake toxin and amiloride
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE, Acid-sensing ion channel 1, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
1AOK
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BU of 1aok by Molmil
VIPOXIN COMPLEX
Descriptor: ACETATE ION, VIPOXIN COMPLEX
Authors:Perbandt, M, Wilson, J.C, Eschenburg, S, Betzel, C.
Deposit date:1997-07-07
Release date:1998-01-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of vipoxin at 2.0 A: an example of regulation of a toxic function generated by molecular evolution.
FEBS Lett., 412, 1997
3O3E
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BU of 3o3e by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2.1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-07-23
Release date:2010-12-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3B
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BU of 3o3b by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1.1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-07-23
Release date:2010-12-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
1TMC
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BU of 1tmc by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF A CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE MISSING THE ALPHA3 DOMAIN OF THE HEAVY CHAIN
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68), DECAMERIC PEPTIDE (EVAPPEYHRK)
Authors:Collins, E.J, Garboczi, D.N, Karpusas, M.N, Wiley, D.C.
Deposit date:1994-12-19
Release date:1995-03-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Proc.Natl.Acad.Sci.USA, 92, 1995
2ZP4
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BU of 2zp4 by Molmil
Carboxylic ester hydrolase, single mutant h48n of bovine pancreatic pla2 enzyme
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Kanaujia, S.P, Sekar, K.
Deposit date:2008-06-27
Release date:2008-11-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures and molecular-dynamics studies of three active-site mutants of bovine pancreatic phospholipase A(2)
Acta Crystallogr.,Sect.D, 64, 2008
3VC0
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BU of 3vc0 by Molmil
Crystal structure of Taipoxin beta subunit isoform 1
Descriptor: Phospholipase A2 homolog, taipoxin beta chain
Authors:Cendron, L, Micetic, I, Polverino de Laureto, P, Beltramini, M, Paoli, M.
Deposit date:2012-01-03
Release date:2012-07-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of trimeric phospholipase A(2) neurotoxin from the Australian taipan snake venom.
Febs J., 279, 2012
6CE2
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BU of 6ce2 by Molmil
Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Basic phospholipase A2 homolog 1
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.
Sci Rep, 8, 2018
3VBZ
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BU of 3vbz by Molmil
Crystal structure of Taipoxin beta subunit isoform 2
Descriptor: Phospholipase A2 homolog, taipoxin beta chain
Authors:Cendron, L, Micetic, I, Polverino, P, Beltramini, M, Paoli, M.
Deposit date:2012-01-03
Release date:2012-07-25
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural analysis of trimeric phospholipase A(2) neurotoxin from the Australian taipan snake venom.
Febs J., 279, 2012
4G5I
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BU of 4g5i by Molmil
Crystal Structure of Porcine pancreatic PlA2 in complex with DBP
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Prasanth, G.K, Naveen, C.D, Mandal, P.K, Karthe, P, Haridas, M, Sadasivan, C.
Deposit date:2012-07-18
Release date:2012-11-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Porcine pancreatic PlA2 in complex with DBP
TO BE PUBLISHED
1OQS
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BU of 1oqs by Molmil
Crystal Structure of RV4/RV7 Complex
Descriptor: Phospholipase A2 RV-4, Phospholipase A2 RV-7
Authors:Perbandt, M, Betzel, C.
Deposit date:2003-03-11
Release date:2003-09-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the heterodimeric neurotoxic complex viperotoxin F (RV-4/RV-7) from the venom of Vipera russelli formosensis at 1.9 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1TP2
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BU of 1tp2 by Molmil
Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
Descriptor: ACETIC ACID, N-TRIDECANOIC ACID, Phospholipase A2 VRV-PL-VIIIa, ...
Authors:Singh, N, Jabeen, T, Sharma, S, Singh, T.P.
Deposit date:2004-06-15
Release date:2004-06-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
To be Published
8AEL
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BU of 8ael by Molmil
SYNJ2BP complex with a synthetic Vangl2 peptide (3mer).
Descriptor: CALCIUM ION, GLY-GLY-GLY-THR-SER-VAL, GLYCEROL, ...
Authors:Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G.
Deposit date:2022-07-13
Release date:2023-08-16
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide.
To Be Published
8DND
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BU of 8dnd by Molmil
Crystal structure of Bothrops pirajai Piratoxin-I (PrTX-I) and synthetic inhibitor Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog piratoxin-1, SULFATE ION
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2022-07-11
Release date:2023-08-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.018 Å)
Cite:Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib.
Biochimie, 207, 2023

238582

数据于2025-07-09公开中

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