3O3E

Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2.1

Summary for 3O3E

• Entry DOI: 10.2210/pdb3o3e/pdb
• Related: 2GT9 3O3A 3O3B 3O3D
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Peptidomimetic ELA-2.1, ... (5 entities in total)
• Functional Keywords: mart peptides, nonapeptide, mhc class i, hla-a2, peptidomimetics, cross-reactivity, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 6
• Total formula weight: 89733.79

Authors

Borbulevych, O.Y.,Baker, B.M. (deposition date: 2010-07-23, release date: 2010-12-08, Last modification date: 2023-11-15)

• Primary citation: Douat-Casassus, C.,Borbulevych, O.,Tarbe, M.,Gervois, N.,Jotereau, F.,Baker, B.M.,Quideau, S.; Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.; J.Med.Chem., 53:7061-7066, 2010; PubMed: 20806940; DOI: 10.1021/jm100683p

Experimental method

X-RAY DIFFRACTION (1.85 Å)