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5J3F
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BU of 5j3f by Molmil
NMR solution structure of [Rp, Rp]-PT dsDNA
Descriptor: DNA (5'-D(*CP*GP*(RSG)P*CP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*(RSG)P*CP*CP*G)-3')
Authors:Lan, W, Hu, Z, Cao, C.
Deposit date:2016-03-30
Release date:2016-11-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural investigation into physiological DNA phosphorothioate modification
Sci Rep, 6, 2016
1UUG
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BU of 1uug by Molmil
ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE:INHIBITOR COMPLEX WITH WILD-TYPE UDG AND WILD-TYPE UGI
Descriptor: URACIL-DNA GLYCOSYLASE, URACIL-DNA GLYCOSYLASE INHIBITOR
Authors:Mol, C.D, Arvai, A.S, Putnam, C.D, Tainer, J.A.
Deposit date:1998-10-31
Release date:1999-03-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase
J.Mol.Biol., 287, 1999
5J3G
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BU of 5j3g by Molmil
Solution NMR structure of PT-free dsDNA from Streptomyces lividans
Descriptor: DNA (5'-D(*CP*GP*GP*CP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*GP*CP*CP*G)-3')
Authors:Lan, W, Cao, C.
Deposit date:2016-03-30
Release date:2016-06-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural investigation into physiological DNA phosphorothioate modification
Sci Rep, 6, 2016
6F57
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BU of 6f57 by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA
Descriptor: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ...
Authors:Zhang, Z.M, Song, J.
Deposit date:2017-12-01
Release date:2018-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
4LVL
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BU of 4lvl by Molmil
MobM Relaxase Domain (MOBV; Mob_Pre) bound to plasmid pMV158 oriT DNA (22nt+3'Thiophosphate). Mn-bound crystal structure at pH 6.8
Descriptor: CHLORIDE ION, DNA (5'-D(*AP*CP*TP*TP*TP*AP*T)-3'), DNA (5'-D(*AP*TP*AP*AP*AP*GP*TP*AP*TP*AP*GP*TP*GP*TP*GP*(TS6))-3'), ...
Authors:Pluta, R, Boer, D.R, Coll, M.
Deposit date:2013-07-26
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8XIH
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BU of 8xih by Molmil
protein-DNA complex
Descriptor: DNA (5'-D(P*AP*TP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*AP*TP*TP*TP*GP*T)-3'), ...
Authors:Li, Z.
Deposit date:2023-12-19
Release date:2024-12-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:protein-DNA complex
To Be Published
7XKM
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BU of 7xkm by Molmil
Crystal structure of DNA-Ag(I) rod comprising a one-dimensional array of 11 silver ions
Descriptor: DNA (5'-D(*CP*GP*CP*GP*CP*(BRU)P*CP*(BRU)P*CP*GP*CP*G)-3'), SILVER ION
Authors:Kondo, J, Ono, A, Atsugi, T.
Deposit date:2022-04-20
Release date:2022-07-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Novel Ag I -DNA Rod Comprising a One-Dimensional Array of 11 Silver Ions within a Double Helical Structure.
Angew.Chem.Int.Ed.Engl., 61, 2022
3O59
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BU of 3o59 by Molmil
DNA polymerase D large subunit DP2(1-300) from Pyrococcus horikoshii
Descriptor: DNA polymerase II large subunit
Authors:Yokoyama, H, Shen, Y, Matsui, I.
Deposit date:2010-07-28
Release date:2011-01-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel structure of an N-terminal domain that is crucial for the dimeric assembly and DNA-binding of an archaeal DNA polymerase D large subunit from Pyrococcus horikoshii
Febs Lett., 585, 2011
9C5Q
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BU of 9c5q by Molmil
Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*CP*GP*GP*G)-3'), DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-06-06
Release date:2024-06-26
Last modified:2025-04-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for Pol theta-helicase DNA binding and microhomology-mediated end-joining.
Nat Commun, 16, 2025
7WAZ
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BU of 7waz by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at ts loading state
Descriptor: NTS-DNA, RNA (115-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
8Y0B
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BU of 8y0b by Molmil
Crystal structure of FnCas12a in complex with pre-crRNA and 12nt target DNA
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*AP*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP*GP*AP*CP*T)-3'), DNA (5'-D(P*AP*GP*TP*CP*CP*TP*TP*TP*AP*GP*AP*TP*A)-3'), ...
Authors:Lin, X, Chen, J, Liu, L.
Deposit date:2024-01-22
Release date:2025-01-01
Last modified:2025-02-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems.
Nucleic Acids Res., 53, 2025
8Y0C
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BU of 8y0c by Molmil
Crystal structure of FnCas12a in complex with pre-crRNA and 18nt target DNA
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (27-MER), DNA (5'-D(P*AP*GP*TP*CP*CP*TP*TP*TP*AP*CP*T)-3'), ...
Authors:Chen, J, Liu, L.
Deposit date:2024-01-22
Release date:2025-01-01
Last modified:2025-02-19
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems.
Nucleic Acids Res., 53, 2025
8VXY
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BU of 8vxy by Molmil
Structure of HamA(E138A,K140A)B-plasmid DNA complex from the Escherichia coli Hachiman defense system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HamA, HamB, ...
Authors:Tuck, O.T, Hu, J.J, Doudna, J.A.
Deposit date:2024-02-06
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
8W0A
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BU of 8w0a by Molmil
Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-02-13
Release date:2024-06-26
Last modified:2025-04-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for Pol theta-helicase DNA binding and microhomology-mediated end-joining.
Nat Commun, 16, 2025
6W3N
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BU of 6w3n by Molmil
APE1 exonuclease substrate complex D148E
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(C7R))-3'), ...
Authors:Freudenthal, B.D, Whitaker, A.M.
Deposit date:2020-03-09
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Molecular and structural characterization of disease-associated APE1 polymorphisms.
DNA Repair (Amst.), 91-92, 2020
6W3U
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BU of 6w3u by Molmil
APE1 exonuclease substrate complex R237C
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Freudenthal, B.D, Whitaker, A.M.
Deposit date:2020-03-09
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular and structural characterization of disease-associated APE1 polymorphisms.
DNA Repair (Amst.), 91-92, 2020
6W2P
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BU of 6w2p by Molmil
APE1 endonuclease product complex L104R
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Freudenthal, B.D, Whitaker, A.M.
Deposit date:2020-03-06
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Molecular and structural characterization of disease-associated APE1 polymorphisms.
DNA Repair (Amst.), 91-92, 2020
6W0Q
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BU of 6w0q by Molmil
APE1 endonuclease product complex D148E
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
Authors:Freudenthal, B.D, Whitaker, A.M.
Deposit date:2020-03-02
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Molecular and structural characterization of disease-associated APE1 polymorphisms.
DNA Repair (Amst.), 91-92, 2020
6W43
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BU of 6w43 by Molmil
APE1 AP-endonuclease product complex R237C
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Freudenthal, B.D, Whitaker, A.M.
Deposit date:2020-03-10
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Molecular and structural characterization of disease-associated APE1 polymorphisms.
DNA Repair (Amst.), 91-92, 2020
8XC7
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BU of 8xc7 by Molmil
Structure of LL-D49194-alpha-1 covalently bound to guanosine-2'-fluorinated d(AACCGGTT)2
Descriptor: DNA (5'-D(*AP*AP*CP*CP*2''F-GP*2''F-GP*TP*T)-3'), LL-D49194alpha1
Authors:Gao, R.Q, Tang, G.L, Cao, C.
Deposit date:2023-12-08
Release date:2024-12-04
Last modified:2024-12-11
Method:SOLUTION NMR
Cite:Different DNA Binding and Damage Mode between Anticancer Antibiotics Trioxacarcin A and LL-D49194 alpha 1.
Jacs Au, 4, 2024
3NDH
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BU of 3ndh by Molmil
Restriction endonuclease in complex with substrate DNA
Descriptor: ACETATE ION, CHLORIDE ION, DNA (5'-D(*C*CP*AP*TP*CP*GP*CP*GP*TP*AP*C)-3'), ...
Authors:Firczuk, M, Wojciechowski, M, Czapinska, H, Bochtler, M.
Deposit date:2010-06-07
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:DNA intercalation without flipping in the specific ThaI-DNA complex
Nucleic Acids Res., 39, 2011
8DC2
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BU of 8dc2 by Molmil
Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA
Descriptor: CasLambda, DNA NTS, DNA TS, ...
Authors:Al-Shayeb, B, Skopintsev, P, Soczek, K, Doudna, J.
Deposit date:2022-06-15
Release date:2022-12-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Cell, 185, 2022
7WB0
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BU of 7wb0 by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state with flexible H2 domain
Descriptor: NTS-DNA, RNA (115-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7LWA
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BU of 7lwa by Molmil
Human Exonuclease 5 crystal structure (T88E) in complex with ssDNA and Mg
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Exonuclease V, ...
Authors:Tsai, C.L, Tainer, J.A.
Deposit date:2021-02-28
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.
Mol.Cell, 81, 2021
7LW9
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BU of 7lw9 by Molmil
Human Exonuclease 5 crystal structure in complex with ssDNA, Sm, and Na
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*AP*TP*TP*GP*CP*TP*GP*AP*AP*GP*GP*G)-3'), ...
Authors:Tsai, C.L, Tainer, J.A.
Deposit date:2021-02-28
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.
Mol.Cell, 81, 2021

238582

数据于2025-07-09公开中

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