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5IO3
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BU of 5io3 by Molmil
Crystal structure of the legionella pneumophila effector protein RavZ - I422
Descriptor: Uncharacterized protein RavZ
Authors:Kwon, D.H, Kim, L, Kim, B.-W, Hong, S.B, Song, H.K.
Deposit date:2016-03-08
Release date:2016-11-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane
Autophagy, 13, 2017
5VFA
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BU of 5vfa by Molmil
RitR Mutant - C128D
Descriptor: Response regulator
Authors:Han, L, Silvaggi, N.R.
Deposit date:2017-04-07
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
5VFP
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BU of 5vfp by Molmil
Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5IOK
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BU of 5iok by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9cr
Descriptor: (ACE)QTAR(KCR)ST, DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14
Authors:Andrews, F.H, Kuateladze, T.G.
Deposit date:2016-03-08
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The Taf14 YEATS domain is a reader of histone crotonylation.
Nat.Chem.Biol., 12, 2016
1SHW
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BU of 1shw by Molmil
EphB2 / EphrinA5 Complex Structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, Ephrin-A5, ...
Authors:Himanen, J.P, Chumley, M.J, Lackmann, M, Li, C, Barton, W.A, Jeffrey, P.D, Vearing, C, Geleick, D, Feldheim, D.A, Boyd, A.W.
Deposit date:2004-02-26
Release date:2004-05-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
5IOO
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BU of 5ioo by Molmil
Accommodation of massive sequence variation in Nanoarchaeota by the C-type lectin fold
Descriptor: AvpA, MAGNESIUM ION
Authors:Handa, S, Paul, B, Miller, J, Valentine, D, Ghosh, P.
Deposit date:2016-03-08
Release date:2016-11-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.521 Å)
Cite:Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.
Bmc Struct.Biol., 16, 2016
7LP8
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BU of 7lp8 by Molmil
The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476
Descriptor: (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ...
Authors:Cuypers, M.G, Slavish, P.J, Rankovic, Z, White, S.W.
Deposit date:2021-02-11
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476
To Be Published
7LPY
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BU of 7lpy by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
5IOV
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BU of 5iov by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation
Descriptor: 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, GLUTAMIC ACID, GLYCINE, ...
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5VNU
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BU of 5vnu by Molmil
Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Mn-bound FeBMb
Descriptor: MANGANESE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y.
Deposit date:2017-05-01
Release date:2017-08-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.584 Å)
Cite:Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism.
J. Am. Chem. Soc., 139, 2017
7M24
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BU of 7m24 by Molmil
Human carbonic anhydrase II in complex with (R)-rosiglitazone
Descriptor: (R)-ROSIGLITAZONE, Carbonic anhydrase 2, ZINC ION
Authors:Mueller, S.L, Peat, T.S.
Deposit date:2021-03-16
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.
Molecules, 26, 2021
5VNY
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BU of 5vny by Molmil
Crystal structure of DM14-3 domain of Lgd
Descriptor: Lethal (2) giant discs 1, isoform B
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2017-05-01
Release date:2017-06-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Structural Basis for Regulation of ESCRT-III Complexes by Lgd.
Cell Rep, 19, 2017
5IPV
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BU of 5ipv by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1
Descriptor: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
Authors:Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, McHaourab, S.H, Gouaux, E.
Deposit date:2016-03-10
Release date:2016-04-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (9.25 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5VX2
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BU of 5vx2 by Molmil
Mcl-1 in complex with Bim-h3Pc-RT
Descriptor: 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera
Authors:Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E.
Deposit date:2017-05-23
Release date:2017-11-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
7LPZ
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BU of 7lpz by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
5IQA
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BU of 5iqa by Molmil
Aminoglycoside Phosphotransferase (2'')-Ia (CTD of AAC(6')-Ie/APH(2'')-Ia) in complex with GMPPNP and Magnesium
Descriptor: Bifunctional AAC/APH, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Caldwell, S.J, Berghuis, A.M.
Deposit date:2016-03-10
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia.
Structure, 24, 2016
5IQO
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BU of 5iqo by Molmil
Crystal structure of the E. coli type 1 pilus subunit FimG (engineered variant with substitutions Q134E and S138E; N-terminal FimG residues 1-12 truncated) in complex with the donor strand peptide DsF_T4R-T6R-D13N
Descriptor: 1,2-ETHANEDIOL, COBALT (II) ION, PENTAETHYLENE GLYCOL, ...
Authors:Giese, C, Eras, J, Kern, A, Capitani, G, Glockshuber, R.
Deposit date:2016-03-11
Release date:2016-07-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:Accelerating the Association of the Most Stable Protein-Ligand Complex by More than Two Orders of Magnitude.
Angew.Chem.Int.Ed.Engl., 55, 2016
5VIF
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BU of 5vif by Molmil
Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
Descriptor: 2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
Authors:Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H.
Deposit date:2017-04-15
Release date:2017-10-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
7LI1
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BU of 7li1 by Molmil
Crystal structure of holo Moraxella catarrhalis ferric binding protein A in an open conformation
Descriptor: CARBONATE ION, FE (III) ION, Fe(3+) ABC transporter substrate-binding protein
Authors:Chan, C, Ng, D, Fraser, M.E, Schryvers, A.B.
Deposit date:2021-01-26
Release date:2022-02-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens.
Biometals, 2022
5IR3
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BU of 5ir3 by Molmil
Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain
Descriptor: ACETATE ION, Ig lambda chain V-VI region AR
Authors:Hernandez-Santoyo, A, Rodriguez-Romero, A.
Deposit date:2016-03-11
Release date:2017-06-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Stabilizing an amyloidogenic lambda 6 light chain variable domain.
FEBS J., 284, 2017
7LRR
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BU of 7lrr by Molmil
Co-bound crystal structure of the engineered cyt cb562 variant, DiCyt2, crystallized in the presence of Cu(II) (M1) and Co(II) (M2)
Descriptor: COBALT (II) ION, HEME C, Soluble cytochrome b562
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-02-17
Release date:2022-02-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Overcoming universal restrictions on metal selectivity by protein design.
Nature, 603, 2022
5IMJ
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BU of 5imj by Molmil
Crystal structure of a Z-ring associated protein from Escherichia coli
Descriptor: Cell division protein ZapD, SULFATE ION
Authors:Choi, H, Yoon, H.J, Lee, H.H.
Deposit date:2016-03-06
Release date:2017-03-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of ZapD, a positive regulator of Z-ring formation during bacterial cytokinesis
To Be Published
7LSL
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BU of 7lsl by Molmil
Cu-bound crystal structure of the engineered cyt cb562 variant, DiCyt2 - H63A, crystallized in the presence of Ni(II)
Descriptor: HEME C, NICKEL (II) ION, Soluble cytochrome b562
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-02-18
Release date:2022-02-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure-guided metal selectivity in malleable protein interface mediated by single disulfide bond
To Be Published
5IMQ
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BU of 5imq by Molmil
Structure of ribosome bound to cofactor at 3.8 angstrom resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G.
Deposit date:2016-03-06
Release date:2016-05-18
Last modified:2025-09-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
J.Biol.Chem., 291, 2016
5IRO
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BU of 5iro by Molmil
Crystal structure of a complex between the Human adenovirus type 4 E3-19K protein and MHC class molecule HLA-A2/TAX
Descriptor: Beta-2-microglobulin, E3 19 kDa protein, HLA class I histocompatibility antigen, ...
Authors:Li, L, Bouvier, M.
Deposit date:2016-03-14
Release date:2016-08-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure of the Adenovirus Type 4 (Species E) E3-19K/HLA-A2 Complex Reveals Species-Specific Features in MHC Class I Recognition.
J Immunol., 197, 2016

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数据于2025-10-22公开中

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