5IPV
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1
Summary for 5IPV
Entry DOI | 10.2210/pdb5ipv/pdb |
Related | 5IOU 5IOV 5IPQ 5IPR 5IPS 5IPT 5IPU |
EMDB information | 8097 8098 8101 8102 8103 8104 8105 8106 |
Descriptor | N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B (2 entities in total) |
Functional Keywords | ligand-gated ion channel, synaptic transmission, signaling protein |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 4 |
Total formula weight | 371771.95 |
Authors | Zhu, S.,Stein, A.R.,Yoshioka, C.,Lee, C.H.,Goehring, A.,McHaourab, S.H.,Gouaux, E. (deposition date: 2016-03-10, release date: 2016-04-20, Last modification date: 2024-03-06) |
Primary citation | Zhu, S.,Stein, R.A.,Yoshioka, C.,Lee, C.H.,Goehring, A.,Mchaourab, H.S.,Gouaux, E. Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165:704-714, 2016 Cited by PubMed: 27062927DOI: 10.1016/j.cell.2016.03.028 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (9.25 Å) |
Structure validation
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