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5WOU
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BU of 5wou by Molmil
Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder
Descriptor: 1,2-ETHANEDIOL, GUK-holder, isoform A, ...
Authors:Caria, S, Kvansakul, M.
Deposit date:2017-08-03
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large.
J. Biol. Chem., 293, 2018
5M0B
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BU of 5m0b by Molmil
Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with a short-chained N-(2-aminoethyl)isoquinoline-5-sulfonamide) Fasudil-derivative (Ligand 03)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, METHANOL, N-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDE, ...
Authors:Wienen-Schmidt, B, Heine, A, Klebe, G.
Deposit date:2016-10-04
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.506 Å)
Cite:Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with different Fasudil-derivatives
To Be Published
4MMY
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BU of 4mmy by Molmil
Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ...
Authors:van Agthoven, J, Xiong, J, Arnaout, M.A.
Deposit date:2013-09-09
Release date:2014-03-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.183 Å)
Cite:Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin.
Nat.Struct.Mol.Biol., 21, 2014
5LQJ
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BU of 5lqj by Molmil
Crystal Structure of COMT in complex with 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole
Descriptor: 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole, CHLORIDE ION, Catechol O-methyltransferase, ...
Authors:Ehler, A, Lerner, C, Rudolph, M.G.
Deposit date:2016-08-17
Release date:2016-09-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal Structure of COMT in complex with 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole
To be published
2ZQE
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BU of 2zqe by Molmil
Crystal structure of the Smr domain of Thermus thermophilus MutS2
Descriptor: MutS2 protein
Authors:Fukui, K, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2008-08-08
Release date:2008-09-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression
J.Biol.Chem., 283, 2008
5LR6
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BU of 5lr6 by Molmil
Crystal Structure of COMT in complex with [3-(2,4-dimethyl-1,3-thiazol-5-yl)-1H-pyrazol-5-yl]-(4-phenylpiperazin-1-yl)methanone
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Catechol O-methyltransferase, ...
Authors:Ehler, A, Lerner, C, Rudolph, M.G.
Deposit date:2016-08-18
Release date:2016-08-31
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of COMT in complex with [3-(2,4-dimethyl-1,3-thiazol-5-yl)-1H-pyrazol-5-yl]-(4-phenylpiperazin-1-yl)methanone
To be published
6HJP
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BU of 6hjp by Molmil
Structure of Influenza Hemagglutinin ectodomain (A/duck/Alberta/35/76) in complex with FISW84 Fab Fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of FISW84 Fab Fragment, Hemagglutinin, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5WV7
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BU of 5wv7 by Molmil
Crystal structure of d(CCGGGGTACCCCGG)2 at 1.4A resolution
Descriptor: DNA (5'-D(*CP*CP*GP*GP*GP*GP*TP*AP*CP*CP*CP*CP*GP*G)-3')
Authors:Karthik, S, Thirugnanasambandam, A, Mandal, P.K, Gautham, N.
Deposit date:2016-12-22
Release date:2017-05-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.406 Å)
Cite:Crystal structure of d(CCGGGGTACCCCGG)2 at 1.4 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5M0U
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BU of 5m0u by Molmil
Apostructure structure of cAMP-dependent Protein Kinase (PKA) from CHO cells with a peptidic inhibitor fragment
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, METHANOL, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Wienen-Schmidt, B, Heine, A, Klebe, G.
Deposit date:2016-10-05
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.667 Å)
Cite:Cocrystal structure of cAMP-dependent Protein Kinase (PKA)
To Be Published
1NO8
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BU of 1no8 by Molmil
SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN
Descriptor: ALY
Authors:Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E.
Deposit date:2003-01-15
Release date:2003-08-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional Regulatory and mRNA Nuclear Export Processes
Biochemistry, 42, 2003
2B2W
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BU of 2b2w by Molmil
Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4
Descriptor: Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
5MHI
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BU of 5mhi by Molmil
cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule (5-chloro-2-methoxyphenyl)methanamine
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (5-chloranyl-2-methoxy-phenyl)methylazanium, DIMETHYL SULFOXIDE, ...
Authors:Siefker, C, Heine, A, Klebe, G.
Deposit date:2016-11-24
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.489 Å)
Cite:A crystallographic fragment study with cAMP-dependent protein kinase A
To Be Published
5MYB
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BU of 5myb by Molmil
Homodimerization of Tie2 Fibronectin-like domains 2 and 3 in space group P21
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ...
Authors:Leppanen, V.-M, Saharinen, P, Alitalo, K.
Deposit date:2017-01-26
Release date:2017-04-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5M71
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BU of 5m71 by Molmil
Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with an (R)-methyl substitued Fasudil-derivative.
Descriptor: 5-[[(2~{R})-2-methyl-1,4-diazepan-4-ium-1-yl]sulfonyl]isoquinoline, METHANOL, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Wienen-Schmidt, B, Heine, A, Klebe, G.
Deposit date:2016-10-26
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.488 Å)
Cite:Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with differently methylated Fasudil-derived ligands
To be Published
2B0H
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BU of 2b0h by Molmil
Solution structure of VBS3 fragment of talin
Descriptor: Talin-1
Authors:Gingras, A.R, Vogel, K.P, Steinhoff, H.J, Ziegler, W.H, Patel, B, Emsley, J, Critchley, D.R, Roberts, G.C, Barsukov, I.L.
Deposit date:2005-09-14
Release date:2006-01-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
2B2T
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BU of 2b2t by Molmil
Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3
Descriptor: Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
Authors:Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B57
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BU of 2b57 by Molmil
Guanine Riboswitch C74U mutant bound to 2,6-diaminopurine
Descriptor: 65-MER, 9H-PURINE-2,6-DIAMINE, ACETATE ION, ...
Authors:Gilbert, S.D, Stoddard, C.D, Wise, S.J, Batey, R.T.
Deposit date:2005-09-27
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.
J.Mol.Biol., 359, 2006
5M50
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BU of 5m50 by Molmil
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Descriptor: Calmodulin-regulated spectrin-associated protein 3, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-P, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J.
Deposit date:2016-10-20
Release date:2017-10-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nat. Struct. Mol. Biol., 24, 2017
5WYM
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BU of 5wym by Molmil
Crystal structure of an anti-connexin26 scFv
Descriptor: anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain
Authors:Li, S, Xu, L.
Deposit date:2017-01-13
Release date:2018-01-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
Front Mol Neurosci, 10, 2017
1MJG
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BU of 1mjg by Molmil
CRYSTAL STRUCTURE OF BIFUNCTIONAL CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE(CODH/ACS) FROM MOORELLA THERMOACETICA (F. CLOSTRIDIUM THERMOACETICUM)
Descriptor: ACETATE ION, CARBON MONOXIDE DEHYDROGENASE BETA SUBUNIT, COPPER (I) ION, ...
Authors:Doukov, T.I, Iverson, T.M, Seravalli, J, Ragsdale, S.W, Drennan, C.L.
Deposit date:2002-08-27
Release date:2003-01-28
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase
Science, 298, 2002
7WZC
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BU of 7wzc by Molmil
An open conformation Form2 of switch II for RhoA GDP-bound state
Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jiang, H, Luo, C.
Deposit date:2022-02-17
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.79944921 Å)
Cite:A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region.
J.Struct.Biol., 215, 2023
7WZA
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BU of 7wza by Molmil
An open conformation Form 1 of switch II for RhoA
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
Authors:Jiang, H, Luo, C.
Deposit date:2022-02-17
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.50028777 Å)
Cite:A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region.
J.Struct.Biol., 215, 2023
5LCQ
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BU of 5lcq by Molmil
Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with long-chain Fasudil-derivative (Ligand 05)
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, METHANOL, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Wienen-Schmidt, B, Heine, A, Klebe, G.
Deposit date:2016-06-22
Release date:2018-01-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.423 Å)
Cite:Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with different Fasudil-derivatives
To Be Published
5ZBS
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BU of 5zbs by Molmil
Crystal Structure of Kinesin-3 KIF13B motor Y73C mutant
Descriptor: Kinesin family member 13B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ren, J.Q, Wang, S, Feng, W.
Deposit date:2018-02-12
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement.
J. Mol. Biol., 430, 2018
5LQA
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BU of 5lqa by Molmil
rat catechol O-methyltransferase at high pH in complex with a bisubstrate inhibitor
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Catechol O-methyltransferase, ...
Authors:Ehler, A, Ellermann, M, Rudolph, M.G.
Deposit date:2016-08-16
Release date:2016-10-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:rat catechol O-methyltransferase at high pH in complex with a bisubstrate inhibitor
To be published

224004

数据于2024-08-21公开中

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