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5LQJ

Crystal Structure of COMT in complex with 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole

Summary for 5LQJ
Entry DOI10.2210/pdb5lqj/pdb
DescriptorCatechol O-methyltransferase, SODIUM ION, 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole, ... (6 entities in total)
Functional Keywordsmethyltransferase, neurotransmitter degradation, catechol, transferase
Biological sourceRattus norvegicus (Norway Rat)
Cellular locationIsoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
Total number of polymer chains4
Total formula weight99917.11
Authors
Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-17, release date: 2016-09-28, Last modification date: 2024-05-01)
Primary citationLerner, C.,Rudolph, M.G.
Crystal Structure of COMT in complex with 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole
To be published,
Experimental method
X-RAY DIFFRACTION (2.41 Å)
Structure validation

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