5LQJ
Crystal Structure of COMT in complex with 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole
Summary for 5LQJ
| Entry DOI | 10.2210/pdb5lqj/pdb |
| Descriptor | Catechol O-methyltransferase, SODIUM ION, 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole, ... (6 entities in total) |
| Functional Keywords | methyltransferase, neurotransmitter degradation, catechol, transferase |
| Biological source | Rattus norvegicus (Norway Rat) |
| Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
| Total number of polymer chains | 4 |
| Total formula weight | 99917.11 |
| Authors | Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-17, release date: 2016-09-28, Last modification date: 2024-05-01) |
| Primary citation | Lerner, C.,Rudolph, M.G. Crystal Structure of COMT in complex with 3-cyclopropyl-5-methyl-4-phenyl-1,2,4-triazole To be published, |
| Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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