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1J1U
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BU of 1j1u by Molmil
Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine
Descriptor: MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ...
Authors:Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-12-17
Release date:2003-06-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion
NAT.STRUCT.BIOL., 10, 2003
2X1M
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BU of 2x1m by Molmil
Crystal structure of Mycobacterium smegmatis methionyl-tRNA synthetase in complex with methionine
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DIHYDROGENPHOSPHATE ION, METHIONINE, ...
Authors:Ingvarsson, H, Jones, T.A, Unge, T.
Deposit date:2009-12-31
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Flexibility and Communication within the Structure of the Mycobacterium Smegmatis Methionyl-tRNA Synthetase.
FEBS J., 277, 2010
2X1L
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BU of 2x1l by Molmil
Crystal structure of Mycobacterium smegmatis methionyl-tRNA synthetase in complex with methionine and adenosine
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ADENOSINE, DIHYDROGENPHOSPHATE ION, ...
Authors:Ingvarsson, H, Jones, T.A, Unge, T.
Deposit date:2009-12-31
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Flexibility and Communication within the Structure of the Mycobacterium Smegmatis Methionyl-tRNA Synthetase.
FEBS J., 277, 2010
1IL2
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BU of 1il2 by Molmil
Crystal Structure of the E. coli Aspartyl-tRNA Synthetase:Yeast tRNAasp:aspartyl-Adenylate Complex
Descriptor: ASPARTYL TRANSFER RNA, ASPARTYL-ADENOSINE-5'-MONOPHOSPHATE, ASPARTYL-TRNA SYNTHETASE, ...
Authors:Moulinier, L, Eiler, S, Eriani, G, Gangloff, J, Thierry, J.C, Gabriel, K, McClain, W.H, Moras, D.
Deposit date:2001-05-07
Release date:2001-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of an AspRS-tRNA(Asp) complex reveals a tRNA-dependent control mechanism.
EMBO J., 20, 2001
2XC7
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BU of 2xc7 by Molmil
Solution Structure of PHAX-RBD in complex with ssRNA
Descriptor: 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN
Authors:Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M.
Deposit date:2010-04-18
Release date:2010-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
1ZH0
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BU of 1zh0 by Molmil
Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-(2-NAPHTHYL)-ALANINE, Tyrosyl-tRNA synthetase
Authors:Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G.
Deposit date:2005-04-22
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
1TYD
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BU of 1tyd by Molmil
STRUCTURE OF TYROSYL-TRNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor: TYROSINE, TYROSYL-tRNA SYNTHETASE
Authors:Brown, K.A, De Meester, P, Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
3KT6
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BU of 3kt6 by Molmil
Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with Trp
Descriptor: SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ...
Authors:Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
3KT0
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Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase.
Descriptor: (2S)-1-{[(2S)-3-(2-methoxyethoxy)-2-methylpropyl]oxy}propan-2-amine, Tryptophanyl-tRNA synthetase, cytoplasmic
Authors:Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2025-05-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
3KT8
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BU of 3kt8 by Molmil
Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with L-tryptophanamide
Descriptor: L-TRYPTOPHANAMIDE, SULFATE ION, Tryptophanyl-tRNA synthetase, ...
Authors:Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
3KT3
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BU of 3kt3 by Molmil
Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with TrpAMP
Descriptor: SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase, ...
Authors:Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res., 38, 2010
6L4Q
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BU of 6l4q by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-B
Descriptor: (3R)-3-[[(3R)-3-methylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase
Authors:Babbar, P, Sharma, A, Manickam, Y, Mishra, S, Harlos, K.
Deposit date:2019-10-19
Release date:2021-05-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B
Chembiochem, 2021
6L3Y
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BU of 6l3y by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-C
Descriptor: (3R)-3-[[(3S)-3-ethylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase, ...
Authors:Babbar, P, Sharma, A, Mishra, S, Manickam, Y, Harlos, K.
Deposit date:2019-10-15
Release date:2021-05-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B
Chembiochem, 2021
4PN0
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BU of 4pn0 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase
Descriptor: mRNA-capping enzyme subunit beta
Authors:Lima, C.D, Doamekpor, S.K.
Deposit date:2014-05-22
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
3QG9
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BU of 3qg9 by Molmil
crystal structure of FBF-2/gld-1 FBEa A7U mutant complex
Descriptor: 1,2-ETHANEDIOL, 5'-R(*UP*GP*UP*GP*CP*CP*UP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Koh, Y.Y, Wang, Y, Qiu, C, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Stacking interactions in PUF-RNA complexes.
Rna, 17, 2011
3QGC
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BU of 3qgc by Molmil
Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa A7U mutant
Descriptor: 5'-R(*UP*GP*UP*GP*CP*CP*UP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stacking interactions in PUF-RNA complexes.
Rna, 17, 2011
3QGB
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BU of 3qgb by Molmil
Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa
Descriptor: 5'-R(*UP*GP*UP*GP*CP*CP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Stacking interactions in PUF-RNA complexes.
Rna, 17, 2011
2KH9
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BU of 2kh9 by Molmil
Solution structure of yeast Prp24-RRM2 bound to a fragment of U6 RNA
Descriptor: 5'-R(*AP*GP*AP*GP*AP*U)-3', U4/U6 snRNA-associated-splicing factor PRP24
Authors:Martin-Tumasz, S.A, Butcher, S.E.
Deposit date:2009-03-27
Release date:2010-03-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24.
Rna, 16, 2010
6WQS
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BU of 6wqs by Molmil
Xanthomonas citri Methionyl-tRNA synthetase in complex with REP8839
Descriptor: 2-{[3-({[4-bromo-5-(1-fluoroethenyl)-3-methylthiophen-2-yl]methyl}amino)propyl]amino}quinolin-4(1H)-one, Methionine--tRNA ligase, ZINC ION
Authors:Mercaldi, G.F, Benedetti, C.E.
Deposit date:2020-04-29
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.
J.Biol.Chem., 296, 2021
6WQT
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BU of 6wqt by Molmil
Xanthomonas citri Methionyl-tRNA synthetase in complex with REP3123
Descriptor: 5-[(3-{[(4R)-6,8-dibromo-3,4-dihydro-2H-1-benzopyran-4-yl]amino}propyl)amino]thieno[3,2-b]pyridin-7(6H)-one, Methionine--tRNA ligase, ZINC ION
Authors:Mercaldi, G.F, Benedetti, C.E.
Deposit date:2020-04-29
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.
J.Biol.Chem., 296, 2021
6X94
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BU of 6x94 by Molmil
An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Zambaldo, C, Koh, M, Nasertorabi, F, Han, G.W, Chatterjee, A, Stevens, R.C, Schultz, P.G.
Deposit date:2020-06-02
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli.
Bioorg.Med.Chem., 28, 2020
4OBY
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BU of 4oby by Molmil
Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition
Descriptor: ARGININE, Arginine--tRNA ligase
Authors:Bi, K, Zheng, Y, Dong, J, Gao, F, Wang, J, Wang, Y, Gong, W.
Deposit date:2014-01-08
Release date:2014-02-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Crystal structure of E. coli arginyl-tRNA synthetase and ligand binding studies revealed key residues in arginine recognition.
Protein Cell, 5, 2014
5XET
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BU of 5xet by Molmil
Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Methionine--tRNA ligase, ...
Authors:Wang, W, Qin, B, Wojdyla, J.A, Wang, M, Gao, X, Cui, S.
Deposit date:2017-04-06
Release date:2018-07-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism.
IUCrJ, 5, 2018
1MB2
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BU of 1mb2 by Molmil
Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation
Descriptor: TRYPTOPHAN, TRYPTOPHAN-TRNA LIGASE
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1M83
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Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in a Closed, Pre-transition State Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-07-24
Release date:2002-12-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003

238582

数据于2025-07-09公开中

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