3KT0

Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase

Summary for 3KT0

Entry DOI	10.2210/pdb3kt0/pdb
Related	3KT3 3KT6 3KT8
Descriptor	Tryptophanyl-tRNA synthetase, cytoplasmic, (2S)-1-{[(2S)-3-(2-methoxyethoxy)-2-methylpropyl]oxy}propan-2-amine (3 entities in total)
Functional Keywords	tryptophanyl-trna synthetase, rossmann fold, s. cerevisiae, aminoacyl-trna synthetase, atp-binding, cytoplasm, ligase, nucleotide-binding, protein biosynthesis
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Cellular location	Cytoplasm: Q12109
Total number of polymer chains	1
Total formula weight	50453.39
Authors	Zhou, M.,Dong, X.,Zhong, C.,Shen, N.,Ding, J. (deposition date: 2009-11-24, release date: 2010-02-16, Last modification date: 2023-11-01)
Primary citation	Zhou, M.,Dong, X.,Shen, N.,Zhong, C.,Ding, J. Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design Nucleic Acids Res., 38:3399-3413, 2010 Cited by PubMed: 20123733 DOI: 10.1093/nar/gkp1254 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation