6X94

An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli

Summary for 6X94

Entry DOI	10.2210/pdb6x94/pdb
Descriptor	Serine--tRNA ligase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, DI(HYDROXYETHYL)ETHER, ... (8 entities in total)
Functional Keywords	serine trna-ligase, protein translation, serine aminoacylation, non-hydrolyzable serine-amp, ligase
Biological source	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Total number of polymer chains	1
Total formula weight	49854.21
Authors	Zambaldo, C.,Koh, M.,Nasertorabi, F.,Han, G.W.,Chatterjee, A.,Stevens, R.C.,Schultz, P.G. (deposition date: 2020-06-02, release date: 2020-11-04, Last modification date: 2023-10-18)
Primary citation	Zambaldo, C.,Koh, M.,Nasertorabi, F.,Han, G.W.,Chatterjee, A.,Stevens, R.C.,Schultz, P.G. An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli. Bioorg.Med.Chem., 28:115662-115662, 2020 Cited by PubMed: 33069069 DOI: 10.1016/j.bmc.2020.115662 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation