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PDB: 10 results

1D2R
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BU of 1d2r by Molmil
2.9 A CRYSTAL STRUCTURE OF LIGAND-FREE TRYPTOPHANYL-TRNA SYNTHETASE: DOMAIN MOVEMENTS FRAGMENT THE ADENINE NUCLEOTIDE BINDING SITE.
Descriptor: PROTEIN (TRYPTOPHANYL TRNA SYNTHETASE)
Authors:Ilyin, V.A, Carter Jr, C.W.
Deposit date:1999-09-27
Release date:2000-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A crystal structure of ligand-free tryptophanyl-tRNA synthetase: domain movements fragment the adenine nucleotide binding site.
Protein Sci., 9, 2000
2OV4
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BU of 2ov4 by Molmil
Crystal structure of B. stearothermophilus tryptophanyl tRNA synthetase in complex with adenosine tetraphosphate
Descriptor: ADENOSINE-5'-TETRAPHOSPHATE, ANILINE, CESIUM ION, ...
Authors:Retailleau, P, Carter Jr, C.W.
Deposit date:2007-02-12
Release date:2007-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Adenosine-5' Tetraphosphate: Evidence for Distributed Use of Catalytic Binding Energy in Amino Acid Activation by Class I Aminoacyl-tRNA Synthetases.
J.Mol.Biol., 369, 2007
3FI0
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BU of 3fi0 by Molmil
Crystal Structure Analysis of B. stearothermophilus Tryptophanyl-tRNA Synthetase Complexed with Tryptophan, AMP, and Inorganic Phosphate
Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, TRYPTOPHAN, ...
Authors:Laowanapiban, P, Kapustina, M, Vonrhein, C, Delarue, M, Koehl, P, Carter Jr, C.W.
Deposit date:2008-12-10
Release date:2009-02-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Proc.Natl.Acad.Sci.Usa, 106, 2009
3FHJ
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Independent saturation of three TrpRS subsites generates a partially-assembled state similar to those observed in molecular simulations
Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, TRYPTOPHAN, ...
Authors:Laowanapiban, P, Kapustina, M, Vonrhein, C, Delarue, M, Koehl, P, Carter Jr, C.W.
Deposit date:2008-12-09
Release date:2009-02-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Proc.Natl.Acad.Sci.Usa, 106, 2009
5EKD
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BU of 5ekd by Molmil
Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.
Descriptor: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Williams, T.L, Carter Jr, C.W.
Deposit date:2015-11-03
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Binding of Mg2+ATP Enhances Inhibition of Human Mitochondrial Tryptophanyl-tRNA Synthetase by Indolmycin
To Be Published
1MAW
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BU of 1maw by Molmil
Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in an Open Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, TRYPTOPHAN-TRNA LIGASE
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1M83
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Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with ATP in a Closed, Pre-transition State Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-07-24
Release date:2002-12-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1MAU
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BU of 1mau by Molmil
Crystal structure of Tryptophanyl-tRNA Synthetase Complexed with ATP and Tryptophanamide in a Pre-Transition state Conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, GLYCEROL, ...
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
1MB2
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BU of 1mb2 by Molmil
Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation
Descriptor: TRYPTOPHAN, TRYPTOPHAN-TRNA LIGASE
Authors:Retailleau, P, Huang, X, Yin, Y, Hu, M, Weinreb, V, Vachette, P, Vonrhein, C, Bricogne, G, Roversi, P, Ilyin, V, Carter Jr, C.W.
Deposit date:2002-08-02
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.Mol.Biol., 325, 2003
5DK4
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Crystal structure analysis of Tryptophanyl-trna synthetase from Bacillus stearothermophilus in complex with indolmycin and Mg*ATP
Descriptor: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Williams, T, Yin, W.Y, Carter Jr, C.W.
Deposit date:2015-09-02
Release date:2015-11-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Selective Inhibition of Bacterial Tryptophanyl-tRNA Synthetases by Indolmycin Is Mechanism-based.
J.Biol.Chem., 291, 2016

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