3UFS
| Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-((5-(3-chloro-5-fluorophenyl)pentyl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-{[5-(3-chloro-5-fluorophenyl)pentyl]oxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2011-11-01 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.971 Å) | Cite: | Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations. J.Am.Chem.Soc., 134, 2012
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4PKA
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3V0P
| Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (4GW) and H-antigen acceptor | Descriptor: | 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
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4POC
| Structure of Triosephosphate Isomerase Wild Type human enzyme. | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | Deposit date: | 2014-02-25 | Release date: | 2015-01-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochim.Biophys.Acta, 1852, 2015
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4PUB
| Crystal structure of Fab DX-2930 | Descriptor: | CHLORIDE ION, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN | Authors: | Abendroth, J, Edwards, T.E, Nixon, A, Ladner, R. | Deposit date: | 2014-03-12 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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3ZE5
| Crystal structure of the integral membrane diacylglycerol kinase - delta4 | Descriptor: | DIACYLGLYCEROL KINASE | Authors: | Li, D, Vogeley, L, Pye, V.E, Lyons, J.A, Aragao, D, Caffrey, M. | Deposit date: | 2012-12-03 | Release date: | 2013-05-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.101 Å) | Cite: | Crystal Structure of the Integral Membrane Diacylglycerol Kinase. Nature, 497, 2013
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3ZE3
| Crystal structure of the integral membrane diacylglycerol kinase - delta7 | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ACETATE ION, ... | Authors: | Li, D, Pye, V.E, Lyons, J.A, Vogeley, L, Aragao, D, Caffrey, M. | Deposit date: | 2012-12-03 | Release date: | 2013-05-22 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structure of the Integral Membrane Diacylglycerol Kinase. Nature, 497, 2013
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3ZE4
| Crystal structure of the integral membrane diacylglycerol kinase - wild-type | Descriptor: | DIACYLGLYCEROL KINASE | Authors: | Li, D, Lyons, J.A, Pye, V.E, Vogeley, L, Aragao, D, Caffrey, M. | Deposit date: | 2012-12-03 | Release date: | 2013-05-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.702 Å) | Cite: | Crystal Structure of the Integral Membrane Diacylglycerol Kinase. Nature, 497, 2013
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3SW2
| X-ray crystal structure of human FXA in complex with 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide | Descriptor: | 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X, ... | Authors: | Klei, H.E. | Deposit date: | 2011-07-13 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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3ZD0
| The Solution Structure of Monomeric Hepatitis C Virus p7 Yields Potent Inhibitors of Virion Release | Descriptor: | P7 PROTEIN | Authors: | Foster, T.L, Sthompson, G, Kalverda, A.P, Kankanala, J, Thompson, J, Barker, A.M, Clarke, D, Noerenberg, M, Pearson, A.R, Rowlands, D.J, Homans, S.W, Harris, M, Foster, R, Griffin, S.D.C. | Deposit date: | 2012-11-23 | Release date: | 2013-09-04 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus P7 as a Viable Class of Antivirals Targeting Virion Release Hepatology, 59, 2014
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2WNK
| Structure of SporoSAG from Toxoplasma gondii | Descriptor: | SPOROZOITE-SPECIFIC SAG PROTEIN | Authors: | Crawford, J, Lamb, E, Grujic, O, Grigg, M.E, Boulanger, M.J. | Deposit date: | 2009-07-09 | Release date: | 2010-02-02 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural and Functional Characterization of Sporosag: A Sag2 Related Surface Antigen from Toxoplasma Gondii. J.Biol.Chem., 285, 2010
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3SDJ
| Structure of RNase-inactive point mutant of oligomeric kinase/RNase Ire1 | Descriptor: | N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, Serine/threonine-protein kinase/endoribonuclease IRE1 | Authors: | Korennykh, A, Korostelev, A, Egea, P, Finer-Moore, J, Zhang, C, Stroud, R, Shokat, K, Walter, P. | Deposit date: | 2011-06-09 | Release date: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structural and functional basis for RNA cleavage by Ire1. Bmc Biol., 9, 2011
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3SGS
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4QXX
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2Z3C
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3S6C
| Structure of human CD1e | Descriptor: | Beta-2-microglobulin, T-cell surface glycoprotein CD1e, membrane-associated, ... | Authors: | Garcia-Alles, L.F, Maveyraud, L, Tranier, S, Mourey, L. | Deposit date: | 2011-05-25 | Release date: | 2011-07-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes. Proc.Natl.Acad.Sci.USA, 108, 2011
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3S6I
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3SY3
| GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis | Descriptor: | GBAA_1210 protein, PHOSPHATE ION | Authors: | Osipiuk, J, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-07-15 | Release date: | 2011-07-27 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis. To be Published
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3WXB
| Crystal structure of NADPH bound carbonyl reductase from chicken fatty liver | Descriptor: | 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized protein | Authors: | Yoneda, K, Sakuraba, H, Fukuda, Y, Sone, T, Araki, T, Ohshima, T. | Deposit date: | 2014-07-29 | Release date: | 2015-07-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure. Febs J., 282, 2015
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2ZU2
| complex structure of CoV 229E 3CL protease with EPDTC | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3C-like proteinase, zinc(II)hydrogensulfide | Authors: | Lee, C.C, Wang, A.H.-J. | Deposit date: | 2008-10-12 | Release date: | 2009-01-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds J.Biol.Chem., 284, 2009
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4QT6
| Crystal structure of the SPRY domain of human HERC1 | Descriptor: | FORMAMIDE, Probable E3 ubiquitin-protein ligase HERC1, UNKNOWN ATOM OR ION | Authors: | Dong, A, Hu, J, Guan, X, Wernimont, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2014-07-07 | Release date: | 2015-01-07 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal structure of the SPRY domain of human HERC1 To be Published
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4Q4Y
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4QDX
| Crystal structure of Antigen 85C-C209G mutant | Descriptor: | Diacylglycerol acyltransferase/mycolyltransferase Ag85C, SULFATE ION | Authors: | Favrot, L, Lajiness, D.H, Ronning, D.R. | Deposit date: | 2014-05-14 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.503 Å) | Cite: | Inactivation of the Mycobacterium tuberculosis Antigen 85 Complex by Covalent, Allosteric Inhibitors. J.Biol.Chem., 289, 2014
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4QEK
| Crystal structure of Antigen 85C-S124A mutant | Descriptor: | Diacylglycerol acyltransferase/mycolyltransferase Ag85C, SULFATE ION, alpha-D-glucopyranose | Authors: | Favrot, L, Lajiness, D.H, Ronning, D.R. | Deposit date: | 2014-05-16 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.299 Å) | Cite: | Inactivation of the Mycobacterium tuberculosis Antigen 85 Complex by Covalent, Allosteric Inhibitors. J.Biol.Chem., 289, 2014
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3KAA
| Structure of Tim-3 in complex with phosphatidylserine | Descriptor: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, Hepatitis A virus cellular receptor 2 | Authors: | Ballesteros, A, Santiago, C, Casasnovas, J.M. | Deposit date: | 2009-10-19 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells. J.Immunol., 184, 2010
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