Crystal structure of Antigen 85C-S124A mutant

Summary for 4QEK

Related4QDO 4QDT 4QDU 4QDX 4QDZ 4QE3
DescriptorDiacylglycerol acyltransferase/mycolyltransferase Ag85C, ALPHA-D-GLUCOSE, SULFATE ION, ... (4 entities in total)
Functional Keywordsdiacylglycerol acyltransferase, mycolyltransferase, transferase
Biological sourceMycobacterium tuberculosis
Cellular locationSecreted (By similarity) P9WQN9
Total number of polymer chains1
Total molecular weight33200.62
Favrot, L.,Lajiness, D.H.,Ronning, D.R. (deposition date: 2014-05-16, release date: 2014-07-09, Last modification date: 2014-09-24)
Primary citation
Favrot, L.,Lajiness, D.H.,Ronning, D.R.
Inactivation of the Mycobacterium tuberculosis Antigen 85 Complex by Covalent, Allosteric Inhibitors.
J.Biol.Chem., 289:25031-25040, 2014
PubMed: 25028518 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M114.582445
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.143603.2%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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