3ZD0
The Solution Structure of Monomeric Hepatitis C Virus p7 Yields Potent Inhibitors of Virion Release
Summary for 3ZD0
Entry DOI | 10.2210/pdb3zd0/pdb |
NMR Information | BMRB: 18863 |
Descriptor | P7 PROTEIN (1 entity in total) |
Functional Keywords | transport protein, antiviral, ion channel, viroporin |
Biological source | HEPATITIS C VIRUS (HCV) |
Total number of polymer chains | 1 |
Total formula weight | 9065.47 |
Authors | Foster, T.L.,Sthompson, G.,Kalverda, A.P.,Kankanala, J.,Thompson, J.,Barker, A.M.,Clarke, D.,Noerenberg, M.,Pearson, A.R.,Rowlands, D.J.,Homans, S.W.,Harris, M.,Foster, R.,Griffin, S.D.C. (deposition date: 2012-11-23, release date: 2013-09-04, Last modification date: 2023-06-14) |
Primary citation | Foster, T.L.,Thompson, G.S.,Kalverda, A.P.,Kankanala, J.,Bentham, M.,Wetherill, L.F.,Thompson, J.,Barker, A.M.,Clarke, D.,Noerenberg, M.,Pearson, A.R.,Rowlands, D.J.,Homans, S.W.,Harris, M.,Foster, R.,Griffin, S.D.C. Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus P7 as a Viable Class of Antivirals Targeting Virion Release Hepatology, 59:408-, 2014 Cited by PubMed: 24022996DOI: 10.1002/HEP.26685 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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