3SDJ
Structure of RNase-inactive point mutant of oligomeric kinase/RNase Ire1
Summary for 3SDJ
Entry DOI | 10.2210/pdb3sdj/pdb |
Related | 3fbv 3SDM |
Descriptor | Serine/threonine-protein kinase/endoribonuclease IRE1, N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine (2 entities in total) |
Functional Keywords | kinase, rnase, ribonuclease, hac1, xbp1, splicing, rna, upr, unfolded protein response, oligomer, transferase, hydrolase |
Biological source | Saccharomyces cerevisiae (Baker's yeast) |
Total number of polymer chains | 14 |
Total formula weight | 730683.95 |
Authors | Korennykh, A.,Korostelev, A.,Egea, P.,Finer-Moore, J.,Zhang, C.,Stroud, R.,Shokat, K.,Walter, P. (deposition date: 2011-06-09, release date: 2011-07-13) |
Primary citation | Korennykh, A.V.,Korostelev, A.A.,Egea, P.F.,Finer-Moore, J.,Stroud, R.M.,Zhang, C.,Shokat, K.M.,Walter, P. Structural and functional basis for RNA cleavage by Ire1. Bmc Biol., 9:47-47, 2011 Cited by PubMed: 21729333DOI: 10.1186/1741-7007-9-47 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.65 Å) |
Structure validation
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