3SDJ

Structure of RNase-inactive point mutant of oligomeric kinase/RNase Ire1

Summary for 3SDJ

Entry DOI	10.2210/pdb3sdj/pdb
Related	3fbv 3SDM
Descriptor	Serine/threonine-protein kinase/endoribonuclease IRE1, N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine (2 entities in total)
Functional Keywords	kinase, rnase, ribonuclease, hac1, xbp1, splicing, rna, upr, unfolded protein response, oligomer, transferase, hydrolase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	14
Total formula weight	730683.95
Authors	Korennykh, A.,Korostelev, A.,Egea, P.,Finer-Moore, J.,Zhang, C.,Stroud, R.,Shokat, K.,Walter, P. (deposition date: 2011-06-09, release date: 2011-07-13)
Primary citation	Korennykh, A.V.,Korostelev, A.A.,Egea, P.F.,Finer-Moore, J.,Stroud, R.M.,Zhang, C.,Shokat, K.M.,Walter, P. Structural and functional basis for RNA cleavage by Ire1. Bmc Biol., 9:47-47, 2011 Cited by PubMed: 21729333 DOI: 10.1186/1741-7007-9-47 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.65 Å)

Structure validation