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6SL7
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BU of 6sl7 by Molmil
The Delta Calcium mutant of ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA
Descriptor: Calponin homology domain protein putative
Authors:Pinotsis, N, Lopez Arolas, A, Djinovic-Carugo, K.
Deposit date:2019-08-18
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin.
Proc.Natl.Acad.Sci.USA, 117, 2020
2L3G
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BU of 2l3g by Molmil
Solution NMR Structure of CH domain of Rho guanine nucleotide exchange factor 7 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4495E
Descriptor: Rho guanine nucleotide exchange factor 7
Authors:Liu, G, Xiao, R, Janjua, H, Acton, T.B, Ciccosanti, A, Shastry, R, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-09-13
Release date:2010-12-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Northeast Structural Genomics Consortium Target HR4495E
To be Published
1BKR
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BU of 1bkr by Molmil
CALPONIN HOMOLOGY (CH) DOMAIN FROM HUMAN BETA-SPECTRIN AT 1.1 ANGSTROM RESOLUTION
Descriptor: SPECTRIN BETA CHAIN
Authors:Djinovic Carugo, K, Banuelos, S, Saraste, M.
Deposit date:1998-07-10
Release date:1998-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural comparisons of calponin homology domains: implications for actin binding.
Structure, 6, 1998
1AOA
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BU of 1aoa by Molmil
N-TERMINAL ACTIN-CROSSLINKING DOMAIN FROM HUMAN FIMBRIN
Descriptor: T-FIMBRIN
Authors:Goldsmith, S.C, Pokala, N, Shen, W, Fedorov, A.A, Matsudaira, P, Almo, S.C.
Deposit date:1997-06-30
Release date:1997-12-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of an actin-crosslinking domain from human fimbrin.
Nat.Struct.Biol., 4, 1997
5A37
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BU of 5a37 by Molmil
Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle.
Descriptor: HUMAN ALPHA-ACTININ-2
Authors:Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M.
Deposit date:2015-05-27
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
5A4B
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BU of 5a4b by Molmil
Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle.
Descriptor: HUMAN ALPHA-ACTININ-2
Authors:Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M.
Deposit date:2015-06-05
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
5A36
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BU of 5a36 by Molmil
Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle.
Descriptor: ALPHA-ACTININ-2
Authors:Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M.
Deposit date:2015-05-27
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
2VZG
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BU of 2vzg by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD2 motif
Descriptor: 1,2-ETHANEDIOL, Alpha-parvin, Paxillin, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-08-01
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
Structure, 16, 2008
2WA5
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BU of 2wa5 by Molmil
Crystal structure of human filamin B actin binding domain at 1.9 Angstroms resolution
Descriptor: CARBONATE ION, FILAMIN-B, SULFATE ION
Authors:Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-02-03
Release date:2009-06-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009
2WA7
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BU of 2wa7 by Molmil
Structure of the M202V mutant of human filamin b actin binding domain at 1.85 Angstrom resolution
Descriptor: CACODYLATE ION, CARBONATE ION, FILAMIN-B
Authors:Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-02-03
Release date:2009-06-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009
2VZD
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BU of 2vzd by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif
Descriptor: 1,2-ETHANEDIOL, ALPHA-PARVIN, GLYCEROL, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-07-31
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
2VZC
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BU of 2vzc by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha parvin
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-07-31
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
2R0O
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BU of 2r0o by Molmil
Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)
Descriptor: Alpha-actinin-4, GLYCEROL
Authors:Lee, S.H, Dominguez, R.
Deposit date:2007-08-20
Release date:2008-02-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis.
J.Mol.Biol., 376, 2008
2QJZ
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BU of 2qjz by Molmil
Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1
Descriptor: Microtubule-associated protein RP/EB family member 1
Authors:Slep, K.C, Vale, R.D.
Deposit date:2007-07-09
Release date:2007-10-02
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1.
Mol.Cell, 27, 2007
5A38
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BU of 5a38 by Molmil
Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle.
Descriptor: ALPHA-ACTININ-2
Authors:Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M.
Deposit date:2015-05-27
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
2RR8
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BU of 2rr8 by Molmil
Solution structure of calponin homology domain of IQGAP1
Descriptor: IQGAP1 protein
Authors:Umemoto, R, Nishida, N, Ogino, S, Shimada, I.
Deposit date:2010-06-09
Release date:2010-09-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the calponin homology domain of human IQGAP1 and its implications for the actin recognition mode.
J.Biomol.Nmr, 48, 2010
5BVR
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BU of 5bvr by Molmil
Actin binding domain of alpha-actinin from Schizosaccharomyces pombe
Descriptor: Alpha-actinin-like protein 1, ZINC ION
Authors:Persson, K, Backman, L, Addario, B.
Deposit date:2015-06-05
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Characterisation of Schizosaccharomyces pombe alpha-actinin.
Peerj, 4, 2016
2WFN
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BU of 2wfn by Molmil
Filamin A actin binding domain
Descriptor: FILAMIN-A, SULFATE ION
Authors:Ruskamo, S, Ylanne, J.
Deposit date:2009-04-09
Release date:2009-10-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the Human Filamin a Actin-Binding Domain
Acta Crystallogr.,Sect.D, 65, 2009
3HOP
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BU of 3hop by Molmil
Structure of the actin-binding domain of human filamin A
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-03
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
3HOR
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BU of 3hor by Molmil
Structure of the actin-binding domain of human filamin A (reduced)
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-03
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
3HOC
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BU of 3hoc by Molmil
Structure of the actin-binding domain of human filamin A mutant E254K
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-02
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
3I6X
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BU of 3i6x by Molmil
Crystal structure of the calponin homology domain of IQGAP1
Descriptor: Ras GTPase-activating-like protein IQGAP1
Authors:Kurella, V.B.
Deposit date:2009-07-07
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
3FER
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BU of 3fer by Molmil
Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.
Descriptor: ACETIC ACID, Filamin-B
Authors:Kuzin, A.P, Abashidze, M, Seetharaman, R, Shastry, R, Sahdev, S, Ciccosanti, C, Xiao, R, Everett, J.K, Huang, Y, Acton, T, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-11-30
Release date:2009-01-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.
To be Published
1QAG
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BU of 1qag by Molmil
Actin binding region of the dystrophin homologue utrophin
Descriptor: UTROPHIN ACTIN BINDING REGION
Authors:Keep, N.H, Winder, S.J, Moores, C.A, Walke, S, Norwood, F.L.M, Kendrick-Jones, J.
Deposit date:1999-03-05
Release date:2000-01-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer
Structure Fold.Des., 7, 1999
1RT8
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BU of 1rt8 by Molmil
CRYSTAL STRUCTURE OF THE ACTIN-CROSSLINKING CORE OF SCHIZOSACCHAROMYCES POMBE FIMBRIN
Descriptor: SULFATE ION, fimbrin
Authors:Klein, M.G, Shi, W, Ramagopal, U, Tseng, Y, Wirtz, D, Kovar, D.R, Staiger, C.J, Almo, S.C.
Deposit date:2003-12-10
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the actin crosslinking core of fimbrin.
Structure, 12, 2004

224931

数据于2024-09-11公开中

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