3F5G
| Crystal structure of death associated protein kinase in complex with ADP and Mg2+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Death-associated protein kinase 1, MAGNESIUM ION | Authors: | McNamara, L.K, Watterson, D.M, Brunzelle, J.S. | Deposit date: | 2008-11-03 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallogr.,Sect.D, 65, 2009
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3F6P
| Crystal Structure of unphosphorelated receiver domain of YycF | Descriptor: | Transcriptional regulatory protein yycF | Authors: | Zhao, H, Tang, L. | Deposit date: | 2008-11-06 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Preliminary crystallographic studies of the regulatory domain of response regulator YycF from an essential two-component signal transduction system. Acta Crystallogr.,Sect.F, 65, 2009
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3FA8
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3F7Z
| X-ray Co-Crystal Structure of Glycogen Synthase Kinase 3beta in Complex with an Inhibitor | Descriptor: | 2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole, Glycogen synthase kinase-3 beta | Authors: | Mol, C.D, Dougan, D.R. | Deposit date: | 2008-11-10 | Release date: | 2009-03-10 | Last modified: | 2024-11-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design, synthesis and structure-activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta. Bioorg.Med.Chem., 17, 2009
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5X3Y
| Refined solution structure of musashi1 RBD2 | Descriptor: | RNA-binding protein Musashi homolog 1 | Authors: | Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M. | Deposit date: | 2017-02-09 | Release date: | 2017-12-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA Molecules, 22, 2017
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3FC2
| PLK1 in complex with BI6727 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bader, G. | Deposit date: | 2008-11-21 | Release date: | 2009-05-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity. Clin.Cancer Res., 15, 2009
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5X5J
| Crystal structure of response regulator AdeR receiver domain | Descriptor: | AdeR | Authors: | Wen, Y. | Deposit date: | 2017-02-16 | Release date: | 2017-08-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.401 Å) | Cite: | Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res., 45, 2017
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3FEN
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3FD7
| Crystal structure of Onconase C87A/C104A-ONC | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Protein P-30, ... | Authors: | Neumann, P, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Stubbs, M.T. | Deposit date: | 2008-11-25 | Release date: | 2009-12-08 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.531 Å) | Cite: | Impact of the C-terminal disulfide bond on the folding and stability of onconase. Chembiochem, 11, 2010
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3FI4
| P38 kinase crystal structure in complex with RO4499 | Descriptor: | (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol, Mitogen-activated protein kinase 14 | Authors: | Kuglstatter, A, Knapp, M, Dunten, P. | Deposit date: | 2008-12-10 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
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3FME
| Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D) | Descriptor: | Dual specificity mitogen-activated protein kinase kinase 6, STAUROSPORINE | Authors: | Filippakopoulos, P, Barr, A, Pike, A.C.W, Berridge, G, Elkins, J, Fedorov, O, Keates, T, Savitsky, P, Soundararajan, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-21 | Release date: | 2009-01-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D) To be Published
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3FMK
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5XWJ
| Crystal Structure of Porcine pancreatic trypsin with tripeptide inhibitor, TRE, at pH 7 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Acetylated-THR-ARG-GLU Inhibitor, CALCIUM ION, ... | Authors: | Saikhedkar, N.S, Bhoite, A.S, Giri, A.P, Kulkarni, K.A. | Deposit date: | 2017-06-29 | Release date: | 2018-03-28 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Tripeptides derived from reactive centre loop of potato type II protease inhibitors preferentially inhibit midgut proteases of Helicoverpa armigera. Insect Biochem. Mol. Biol., 95, 2018
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3FNS
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3FMN
| P38 kinase crystal structure in complex with RO2530 | Descriptor: | 6-(2,4-difluorophenoxy)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine, Mitogen-activated protein kinase 14 | Authors: | Kuglstatter, A, Ghate, M. | Deposit date: | 2008-12-22 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | P38 kinase crystal structure in complex with RO2530 To be Published
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5X7K
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3F78
| Crystal structure of wild type LFA1 I domain complexed with isoflurane | Descriptor: | 1-CHLORO-2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER, GLYCEROL, Integrin alpha-L, ... | Authors: | Zhang, H, Wang, J.-H. | Deposit date: | 2008-11-07 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems. Faseb J., 23, 2009
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3F7M
| Crystal structure of apo Cuticle-Degrading Protease (ver112) from Verticillium psalliotae | Descriptor: | Alkaline serine protease ver112 | Authors: | Liang, L, Lou, Z, Ye, F, Meng, Z, Rao, Z, Zhang, K. | Deposit date: | 2008-11-09 | Release date: | 2009-11-17 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes. Faseb J., 24, 2010
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3EYC
| New crystal structure of human tear lipocalin in complex with 1,4-butanediol in space group P21 | Descriptor: | 1,4-BUTANEDIOL, Lipocalin-1 | Authors: | Breustedt, D.A, Keil, L, Skerra, A. | Deposit date: | 2008-10-20 | Release date: | 2009-10-06 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A new crystal form of human tear lipocalin reveals high flexibility in the loop region and induced fit in the ligand cavity Acta Crystallogr.,Sect.D, 65, 2009
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5XCO
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3FKL
| P38 kinase crystal structure in complex with RO9552 | Descriptor: | Mitogen-activated protein kinase 14, N-cyclopropyl-4-methyl-3-[8-methyl-7-oxo-2-(tetrahydro-2H-pyran-4-ylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]benzamide | Authors: | Kuglstatter, A, Ghate, M. | Deposit date: | 2008-12-17 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
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3F2A
| Crystal structure of human Pim-1 in complex with DAPPA | Descriptor: | (2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-yl]phenyl}prop-2-enoic acid, MAGNESIUM ION, Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Qian, K. | Deposit date: | 2008-10-29 | Release date: | 2009-03-10 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode. J.Med.Chem., 52, 2009
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5XNT
| Structure of CYP106A2 from Bacillus sp. PAMC 23377 | Descriptor: | Cytochrome P450 CYP106, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lee, C.W, Kim, K.-H, Bikash, D, Park, S.-H, Park, H, Oh, T.-J, Lee, J.H. | Deposit date: | 2017-05-24 | Release date: | 2018-04-04 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure and Functional Characterization of a Cytochrome P450 (BaCYP106A2) fromBacillussp. PAMC 23377. J. Microbiol. Biotechnol., 27, 2017
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3FKO
| P38 kinase crystal structure in complex with RO3668 | Descriptor: | 3-(2-chlorophenyl)-6-(2-fluorophenoxy)-2H-indazole, Mitogen-activated protein kinase 14 | Authors: | Kuglstatter, A, Knapp, M. | Deposit date: | 2008-12-17 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
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5XG9
| Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ... | Authors: | Gautam, G, Gourinath, S. | Deposit date: | 2017-04-13 | Release date: | 2017-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition Acta Crystallogr D Struct Biol, 73, 2017
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