PDB: 243531 resultsInfo pagesStatus searchChemie searchBIRD

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6W0B	Open-gate KcsA soaked in 2 mM BaCl2 Descriptor: BARIUM ION, Fab Heavy Chain, Fab Light Chain, ... Authors: Rohaim, A, Gong, L, Li, J. Deposit date: 2020-02-29 Release date: 2020-07-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.604 Å) Cite: Open and Closed Structures of a Barium-Blocked Potassium Channel. J.Mol.Biol., 432, 2020
5VDK	Crystal structure of human WEE2 kinase domain in complex with MK1775 Descriptor: 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, PHOSPHATE ION, Wee1-like protein kinase 2 Authors: Zhu, J.-Y, Schonbrunn, E. Deposit date: 2017-04-03 Release date: 2017-08-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017
5IFZ	Crystal Structure of Ribose-5-phosphate Isomerase from Brucella melitensis 16M Descriptor: Ribose 5-phosphate isomerase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-02-26 Release date: 2016-04-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of Ribose-5-phosphate Isomerase from Brucella melitensis 16M to be published
8VUK	The crystal structure of Brucella abortus FtrB at 1.3 Angstrom resolution Descriptor: EfeO-type cupredoxin-like domain-containing protein, MANGANESE (II) ION Authors: Roy, S, Garcia, B.L. Deposit date: 2024-01-29 Release date: 2025-01-22 Last modified: 2025-08-06 Method: X-RAY DIFFRACTION (1.3 Å) Cite: In Vitro Structural and Functional Studies of a Novel Cupredoxin, FtrB, from Brucella abortus 2308. Acs Omega, 10, 2025
7M3H	Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor Descriptor: 5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid, CALCIUM ION, Hydroxymethylglutaryl-CoA reductase, ... Authors: Bose, S, Steussy, C.N, Stauffacher, C.V. Deposit date: 2021-03-18 Release date: 2022-09-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor To Be Published
6W0M	Human 8-oxoguanine glycosylase crosslinked with oxoG lesion containing DNA Descriptor: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), ... Authors: Shigdel, U, Verdine, G. Deposit date: 2020-03-02 Release date: 2020-09-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.37 Å) Cite: The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
5VDW	Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F1 Descriptor: Cyclic GMP-AMP synthase, ZINC ION, [2-(1,3-thiazol-4-yl)-1H-benzimidazol-1-yl]acetic acid Authors: Byrnes, L.J, Hall, J.D. Deposit date: 2017-04-03 Release date: 2017-09-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.711 Å) Cite: The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017
6W0R	Human 8-oxoguanine glycosylase interrogating fully intrahelical undamaged DNA Descriptor: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*AP*GP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*TP*GP*G)-3'), ... Authors: Shigdel, U, Verdine, G. Deposit date: 2020-03-02 Release date: 2020-09-23 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.35 Å) Cite: The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
5IKD	Asymmetric sulfoxidation by engineering the heme pocket of a dye-decolorizing peroxidase Descriptor: Dye-decolorizing peroxidase, PROTOPORPHYRIN IX CONTAINING FE Authors: Romero, A, Davo-Siguero, I, Martinez, A.T. Deposit date: 2016-03-03 Release date: 2016-07-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.109 Å) Cite: Asymmetric sulfoxidation by engineering the heme pocket of a dye-decolorizing peroxidase Catalysis Science And Technology, 2016
7M4E	DNA Polymerase Lambda, dCTP:At Mg2+ Reaction State Ternary Complex, 120 min Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.903 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
8VVX	Human Aquaporin 2 from 2D electron diffraction data Descriptor: Aquaporin-2 Authors: Vahedi-Faridi, A, Lodowski, D.T, Engel, A, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) Deposit date: 2024-01-31 Release date: 2025-02-05 Method: ELECTRON CRYSTALLOGRAPHY (2.6 Å) Cite: Human Aquaporin 2 from 2D electron diffraction data To Be Published
5VJ0	Crystal Structure of heme-containing DyP Type Peroxidase from Enterobacter lignolyticus Descriptor: Dyp-type peroxidase family, PROTOPORPHYRIN IX CONTAINING FE Authors: Meekins, D.A, Li, P, Geisbrecht, B.V. Deposit date: 2017-04-17 Release date: 2017-08-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects. ACS Catal, 7, 2017
5VJS	De Novo Photosynthetic Reaction Center Protein Equipped with Heme B, a synthetic Zn porphyrin, and Zn(II) cations Descriptor: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Reaction Center Maquette, ... Authors: Ennist, N.M, Dutton, P.L, Stayrook, S.E, Moser, C.C. Deposit date: 2017-04-19 Release date: 2018-04-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2 Å) Cite: De novo protein design of photochemical reaction centers. Nat Commun, 13, 2022
7M45	DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 120 sec Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.889 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
6W15	Crystal structure of tRNA (guanine-N(1)-)-methyltransferase with bound SAH from Mycobacterium smegmatis Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-03-03 Release date: 2020-05-06 Last modified: 2025-10-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of tRNA (guanine-N(1)-)-methyltransferase with bound SAH from Mycobacterium smegmatis to be published
8VHV	Transmembrane AMPA Receptor Regulatory Protein Subunit Gamma 2 Descriptor: Voltage-dependent calcium channel gamma-2 subunit Authors: Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C. Deposit date: 2024-01-02 Release date: 2025-01-22 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structure of transmembrane AMPA receptor regulatory protein subunit gamma 2. Nat Commun, 16, 2025
7M4G	DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 960 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
8VWA	CryoEM Structure of a FtsH Helical Assembly in the Presence of ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH, MAGNESIUM ION, ... Authors: Li, Y, Zhu, J, Zhang, Z, Wang, F, Egelman, E.H, Tezcan, F.A. Deposit date: 2024-01-31 Release date: 2025-01-15 Last modified: 2025-06-11 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Transforming an ATP-dependent enzyme into a dissipative, self-assembling system. Nat.Chem.Biol., 21, 2025
6W1F	Crystal structure of Streptococcus thermophilus SHP pheromone receptor Rgg3 bound to DNA Descriptor: DNA (30-MER), Positive transcriptional regulator MutR family Authors: Neiditch, M.B, Capodagli, G.C. Deposit date: 2020-03-04 Release date: 2020-10-21 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay. Proc.Natl.Acad.Sci.USA, 117, 2020
7M4D	DNA Polymerase Lambda, dCTP:At Ca2+ Ground State Ternary Complex Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.817 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
5IGF	Crystal structure of Staphylococcal nuclease variant Delta+PHS T62H/V66D at cryogenic temperature Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease Authors: Robinson, A.C, Schlessman, J.L, Garcia-Moreno E, B. Deposit date: 2016-02-27 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of Staphylococcal nuclease variant Delta+PHS T62H/V66D at cryogenic temperature To be Published
6W2V	Junction 23, DHR14-DHR18 Descriptor: Junction 23 DHR14-DHR18 Authors: Bick, M.J, Brunette, T.J, Baker, D. Deposit date: 2020-03-08 Release date: 2020-04-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.399 Å) Cite: Modular repeat protein sculpting using rigid helical junctions. Proc.Natl.Acad.Sci.USA, 117, 2020
7M4K	DNA Polymerase Lambda, TTPaS:At Ca2+ Ground State Ternary Complex Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.719 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
8W3M	Crystal Structure of Enterovirus 68 3C Protease with AG7404 at 1.97 Angstroms Descriptor: Peptidase C3, SODIUM ION, ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate Authors: Azzolino, V.N, Shaqra, A.M, Schiffer, C.A. Deposit date: 2024-02-22 Release date: 2025-01-15 Last modified: 2025-02-05 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease. Viruses, 17, 2025
6W37	STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN Descriptor: ORF7a protein Authors: Nelson, C.A, Minasov, G, Shuvalova, L, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2020-03-09 Release date: 2020-04-29 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.9 Å) Cite: STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN To be published

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