7M3H
Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor
Summary for 7M3H
Entry DOI | 10.2210/pdb7m3h/pdb |
Related | 7M1Z |
Descriptor | Hydroxymethylglutaryl-CoA reductase, degradative, 5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | ligands, metabolism, drug target, hmg-coa, mevalonate, prokaryote., antibiotic |
Biological source | Enterococcus faecalis (Streptococcus faecalis) |
Total number of polymer chains | 2 |
Total formula weight | 93238.19 |
Authors | Bose, S.,Steussy, C.N.,Stauffacher, C.V. (deposition date: 2021-03-18, release date: 2022-09-21, Last modification date: 2023-10-18) |
Primary citation | Bose, S.,Steussy, C.N.,Stauffacher, C.V. Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.27 Å) |
Structure validation
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