7M3H
Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hydroxymethylglutaryl-CoA reductase, degradative | polymer | 423 | 46105.6 | 2 | UniProt (A0A4U3MLJ4) Pfam (PF00368) | Enterococcus faecalis (Streptococcus faecalis) | |
| 2 | C, E (A, B) | 5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid | non-polymer | 349.4 | 2 | Chemie (YPV) | |||
| 3 | D, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 973 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92211.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1027.1 | |
| All* | Total formula weight | 93238.2 |
