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8K5B
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BU of 8k5b by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8ODU
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BU of 8odu by Molmil
Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (amphipol)
Descriptor: ATPase GET3, Protein GET2,Protein GET1, ZINC ION
Authors:McDowell, M.A, Wild, K, Sinning, I.
Deposit date:2023-03-09
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The GET insertase exhibits conformational plasticity and induces membrane thinning.
Nat Commun, 14, 2023
8ODV
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BU of 8odv by Molmil
Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (nanodisc)
Descriptor: ATPase GET3, Protein GET2,Protein GET1, ZINC ION
Authors:McDowell, M.A, Wild, K, Sinning, I.
Deposit date:2023-03-09
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:The GET insertase exhibits conformational plasticity and induces membrane thinning.
Nat Commun, 14, 2023
8K0B
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BU of 8k0b by Molmil
Cryo-EM structure of TMEM63C
Descriptor: Calcium permeable stress-gated cation channel 1
Authors:Qin, Y, Yu, D, Dong, J, Dang, S.
Deposit date:2023-07-08
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Cryo-EM structure of TMEM63C suggests it functions as a monomer.
Nat Commun, 14, 2023
8OH7
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BU of 8oh7 by Molmil
Structure of A4M4C bound to (KR)4 Solution backbone structure refined by PCS
Descriptor: Designed Armadillo repeat protein with four internal modules
Authors:Cucuzza, S, Zerbe, O.
Deposit date:2023-03-20
Release date:2023-12-13
Method:SOLUTION NMR
Cite:Unexpected dynamics in femtomolar complexes of binding proteins with peptides.
Nat Commun, 14, 2023
8KAD
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BU of 8kad by Molmil
Crystal structure of an antibody light chain tetramer with 3D domain swapping
Descriptor: Antibody light chain
Authors:Sakai, T, Mashima, T, Kobayashi, N, Ogata, H, Uda, T, Hifumi, E, Hirota, S.
Deposit date:2023-08-02
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping.
Nat Commun, 14, 2023
8KI0
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BU of 8ki0 by Molmil
Crystal structure of the hemophore HasA from Pseudomonas protegens Pf-5 capturing Fe-tetraphenylporphyrin
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Heme acquisition protein HasAp, ...
Authors:Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O.
Deposit date:2023-08-22
Release date:2024-03-27
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom.
Rsc Adv, 14, 2024
8KI1
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BU of 8ki1 by Molmil
Crystal structure of the holo form of the hemophore HasA from Pseudomonas protegens Pf-5
Descriptor: GLYCEROL, Heme acquisition protein HasAp, PHOSPHATE ION, ...
Authors:Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O.
Deposit date:2023-08-22
Release date:2024-03-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom.
Rsc Adv, 14, 2024
8KIF
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BU of 8kif by Molmil
The structure of MmaE with substrate
Descriptor: (3R)-3-(2-hydroxy-2-oxoethylamino)decanoic acid, FE (II) ION, Putative dioxygenase
Authors:Chen, J, Zhou, J.
Deposit date:2023-08-23
Release date:2024-04-17
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Variation in biosynthesis and metal-binding properties of isonitrile-containing peptides produced by Mycobacteria versus Streptomyces.
Acs Catalysis, 14, 2024
8KHT
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BU of 8kht by Molmil
The structure of Rv0097 with substrate
Descriptor: (3R)-3-(2-hydroxy-2-oxoethylamino)decanoic acid, FE (II) ION, Oxidoreductase
Authors:Chen, J, Zhou, J.
Deposit date:2023-08-22
Release date:2024-04-17
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Variation in biosynthesis and metal-binding properties of isonitrile-containing peptides produced by Mycobacteria versus Streptomyces.
Acs Catalysis, 14, 2024
8JQY
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BU of 8jqy by Molmil
Crystal Structure of nucleotide-free mIRGB10
Descriptor: Immunity-related GTPase family member b10
Authors:Ha, H.J, Park, H.H.
Deposit date:2023-06-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Structural basis of IRGB10 oligomerization by GTP hydrolysis.
Front Immunol, 14, 2023
8JQZ
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BU of 8jqz by Molmil
Crystal Structure of GppNHp-bound mIRGB10
Descriptor: Immunity-related GTPase family member b10, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ha, H.J, Park, H.H.
Deposit date:2023-06-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis of IRGB10 oligomerization by GTP hydrolysis.
Front Immunol, 14, 2023
8K7P
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BU of 8k7p by Molmil
Staphylococcus aureus lipase -PSA complex
Descriptor: ACETIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Kitadokoro, J, Kamitani, S, Kitadokoro, K.
Deposit date:2023-07-27
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid.
Febs Open Bio, 14, 2024
7EIU
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BU of 7eiu by Molmil
Crystal structure of Mei2 RRM3 in complex with 8mer meiRNA
Descriptor: GLYCEROL, Meiosis protein mei2, RNA (5'-R(P*UP*UP*CP*UP*GP*C)-3')
Authors:Shen, S.Y, Lv, M.Q.
Deposit date:2021-03-31
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Structural insights reveal the specific recognition of meiRNA by the Mei2 protein.
J Mol Cell Biol, 14, 2022
8K7Q
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BU of 8k7q by Molmil
Staphylococcus aureus lipase S116A inactive mutant-PSA complex
Descriptor: ACETIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Kitadokoro, J, Kamitani, S, Kitadokoro, K.
Deposit date:2023-07-27
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid.
Febs Open Bio, 14, 2024
7EIO
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BU of 7eio by Molmil
Crystal Structure of Mei2 RRM3
Descriptor: GLYCEROL, Meiosis protein mei2, SULFATE ION
Authors:Shen, S.Y, Li, F.D.
Deposit date:2021-03-31
Release date:2022-04-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Structural insights reveal the specific recognition of meiRNA by the Mei2 protein.
J Mol Cell Biol, 14, 2022
8J1T
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BU of 8j1t by Molmil
Local refined cryo-EM structure of Omicron BA.5 RBD in complex with 8-9D Fab
Descriptor: 8-9D heavy chain, 8-9D light chain, Spike protein
Authors:Xiang, Y, Li, R.
Deposit date:2023-04-13
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection.
Nat Commun, 14, 2023
8J6R
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BU of 8j6r by Molmil
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
Descriptor: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
Deposit date:2023-04-26
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8J1E
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BU of 8j1e by Molmil
AtSLAC1 in open state
Descriptor: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein
Authors:Lee, Y, Lee, S.
Deposit date:2023-04-12
Release date:2023-11-22
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
8J2F
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BU of 8j2f by Molmil
Human neutral shpingomyelinase
Descriptor: HEPTANE, MAGNESIUM ION, Sphingomyelin phosphodiesterase 2, ...
Authors:Zhang, S.S.
Deposit date:2023-04-14
Release date:2023-12-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2).
Nat Commun, 14, 2023
8J6Q
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BU of 8j6q by Molmil
Cryo-EM structure of the 3-HB and compound 9n-bound human HCAR2-Gi1 complex
Descriptor: (3R)-3-hydroxybutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, ...
Authors:Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
Deposit date:2023-04-26
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8J6P
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BU of 8j6p by Molmil
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, ...
Authors:Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
Deposit date:2023-04-26
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8JMV
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BU of 8jmv by Molmil
Flagellar fibrils from Bacillus amyloliquefaciens
Descriptor: Flagella
Authors:Cao, Q, Cheng, Y.
Deposit date:2023-06-05
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EM.
Nat Commun, 14, 2023
7DZE
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BU of 7dze by Molmil
Fabp ground state captured by XFELs
Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID
Authors:Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J.
Deposit date:2021-01-25
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
7DZF
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BU of 7dzf by Molmil
Intermediate of FABP with a delay time of 10 ns
Descriptor: Fatty acid-binding protein, liver, PALMITIC ACID
Authors:Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J.
Deposit date:2021-01-25
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022

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数据于2024-09-11公开中

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