9EZC
 
 | | Structure of the extracellular subdomain of a homomeric LRRC8C truncation disease mutant | | Descriptor: | Volume-regulated anion channel subunit LRRC8C | | Authors: | Rutz, S, Quinodoz, M, Peter, V, Garavelli, L, Innes, M.A, Kellenberger, S, Peng, Z, Barone, A, Campos-Xavier, B, Unger, S, Rivolta, C, Dutzler, R, Superti-Furga, A. | | Deposit date: | 2024-04-11 | | Release date: | 2024-11-13 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | De novo variants in LRRC8C resulting in constitutive channel activation cause a human multisystem disorder.
Embo J., 44, 2025
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3C7F
 | | Crystal structure of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from bacillus subtilis in complex with xylotriose. | | Descriptor: | CALCIUM ION, Endo-1,4-beta-xylanase, FORMIC ACID, ... | | Authors: | Vandermarliere, E, Bourgois, T.M, Winn, M.D, Van Campenhout, S, Volckaert, G, Strelkov, S.V, Delcour, J.A, Rabijns, A, Courtin, C.M. | | Deposit date: | 2008-02-07 | | Release date: | 2008-11-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural analysis of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase in complex with xylotetraose reveals a different binding mechanism compared with other members of the same family.
Biochem.J., 418, 2009
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9F6O
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9F6N
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7A43
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7A42
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7A45
 | | CO-bound sperm whale myoglobin measured by serial femtosecond crystallography | | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Mehrabi, P, Schulz, E.C, Buecker, R. | | Deposit date: | 2020-08-19 | | Release date: | 2021-04-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison.
Sci Adv, 7, 2021
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7A44
 | | CO-bound sperm whale myoglobin measured by serial synchrotron crystallography | | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Mehrabi, P, Schulz, E.C, Buecker, R. | | Deposit date: | 2020-08-19 | | Release date: | 2021-04-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison.
Sci Adv, 7, 2021
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3BWY
 | | Crystal Structure of Human 108M Catechol O-methyltransferase bound with S-adenosylmethionine and inhibitor dinitrocatechol | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3,5-DINITROCATECHOL, COMT protein, ... | | Authors: | Rutherford, K, Le Trong, I, Stenkamp, R.E, Parson, W.W. | | Deposit date: | 2008-01-10 | | Release date: | 2008-06-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structures of human 108V and 108M catechol O-methyltransferase.
J.Mol.Biol., 380, 2008
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6CP4
 | | P450CAM D251N MUTANT | | Descriptor: | CAMPHOR, CYTOCHROME P450CAM, GLYCEROL, ... | | Authors: | Li, H, Poulos, T.L. | | Deposit date: | 1998-05-28 | | Release date: | 1998-09-16 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect.
Biochemistry, 37, 1998
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9FA5
 | | Lysozyme structure at room temperature by serial synchrotron crystallography with COC chips | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Lysozyme C, ... | | Authors: | Quereda-Moraleda, I, Grieco, A, Botha, S, Manna, A, Ros, A, Martin-Garcia, J.M. | | Deposit date: | 2024-05-10 | | Release date: | 2025-03-19 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cyclic Olefin Copolymer-Based Fixed-Target Sample Delivery Device for Protein X-ray Crystallography.
Anal.Chem., 96, 2024
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3C5R
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1WT7
 | | Solution structure of BuTX-MTX: a butantoxin-maurotoxin chimera | | Descriptor: | BuTX-MTX | | Authors: | M'Barek, S, Chagot, B, Andreotti, N, Visan, V, Mansuelle, P, Grissmer, S, Marrakchi, M, El Ayeb, M, Sampieri, F, Darbon, H, Fajloun, Z, De Waard, M, Sabatier, J.-M. | | Deposit date: | 2004-11-16 | | Release date: | 2004-11-30 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.
Proteins, 60, 2005
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3C7H
 | | Crystal structure of glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from Bacillus subtilis in complex with AXOS-4-0.5. | | Descriptor: | CALCIUM ION, Endo-1,4-beta-xylanase, FORMIC ACID, ... | | Authors: | Vandermarliere, E, Bourgois, T.M, Winn, M.D, Van Campenhout, S, Volckaert, G, Strelkov, S.V, Delcour, J.A, Rabijns, A, Courtin, C.M. | | Deposit date: | 2008-02-07 | | Release date: | 2008-11-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural analysis of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase in complex with xylotetraose reveals a different binding mechanism compared with other members of the same family.
Biochem.J., 418, 2009
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9C8U
 | | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | | Descriptor: | Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ... | | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | Deposit date: | 2024-06-13 | | Release date: | 2024-09-04 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.
Nat Commun, 15, 2024
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9C8V
 | | Human DNA polymerase alpha/primase - CHAPSO (4 mM) | | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | Deposit date: | 2024-06-13 | | Release date: | 2024-09-04 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.
Nat Commun, 15, 2024
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7X5L
 | | Tir-dsDNA complex, the initial binding state | | Descriptor: | DNA (5'-D(*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*AP*TP*TP*AP*A)-3'), Flax rust resistance protein | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2022-03-04 | | Release date: | 2022-06-01 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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5KET
 | | Structure of the aldo-keto reductase from Coptotermes gestroi | | Descriptor: | Aldo-keto reductase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Liberato, M.L, Campos, B.M, Tramontina, R, Squina, F.M. | | Deposit date: | 2016-06-10 | | Release date: | 2017-01-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | The Coptotermes gestroi aldo-keto reductase: a multipurpose enzyme for biorefinery applications.
Biotechnol Biofuels, 10, 2017
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1DE3
 | | SOLUTION STRUCTURE OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN | | Descriptor: | RIBONUCLEASE ALPHA-SARCIN | | Authors: | Perez-Canadillas, J.M, Campos-Olivas, R, Santoro, J, Lacadena, J, Martinez del Pozo, A, Gavilanes, J.G, Rico, M, Bruix, M. | | Deposit date: | 1999-11-12 | | Release date: | 2000-06-21 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | The highly refined solution structure of the cytotoxic ribonuclease alpha-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity.
J.Mol.Biol., 299, 2000
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2QSQ
 | | Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA) | | Descriptor: | CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 5, GLYCEROL | | Authors: | Le Trong, I, Korotkova, N, Moseley, S.L, Stenkamp, R.E. | | Deposit date: | 2007-07-31 | | Release date: | 2008-01-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation.
Mol.Microbiol., 67, 2008
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4D9Q
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4D9R
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5K8G
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4CNU
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7Y8Y
 | | Structure of Cas7-11-crRNA-tgRNA in complex with TPR-CHAT | | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (37-MER), ... | | Authors: | Wang, S, Guo, M, Zhu, Y, Huang, Z. | | Deposit date: | 2022-06-24 | | Release date: | 2023-06-28 | | Last modified: | 2024-01-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT.
Cell Res., 32, 2022
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