9EZC

Structure of the extracellular subdomain of a homomeric LRRC8C truncation disease mutant

Summary for 9EZC

• Entry DOI: 10.2210/pdb9ezc/pdb
• EMDB information: 50072
• Descriptor: Volume-regulated anion channel subunit LRRC8C (1 entity in total)
• Functional Keywords: anion channel, volume regulation, disease mutation, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 7
• Total formula weight: 334039.59

Authors

Rutz, S.,Quinodoz, M.,Peter, V.,Garavelli, L.,Innes, M.A.,Kellenberger, S.,Peng, Z.,Barone, A.,Campos-Xavier, B.,Unger, S.,Rivolta, C.,Dutzler, R.,Superti-Furga, A. (deposition date: 2024-04-11, release date: 2024-11-13, Last modification date: 2024-11-27)

• Primary citation: Rutz, S.,Quinodoz, M.,Peter, V.,Garavelli, L.,Innes, M.A.,Kellenberger, S.,Peng, Z.,Barone, A.,Campos-Xavier, B.,Unger, S.,Rivolta, C.,Dutzler, R.,Superti-Furga, A.; Genetic activation of Volume-Regulated Anion Channels cause a multisystem disorder; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.41 Å)