9EZC
Structure of the extracellular subdomain of a homomeric LRRC8C truncation disease mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Volume-regulated anion channel subunit LRRC8C | polymer | 414 | 47719.9 | 7 | UniProt (Q8TDW0) Pfam (PF12534) | Homo sapiens (human) | Factor for adipocyte differentiation 158,Leucine-rich repeat-containing protein 8C |
Sequence modifications
A, B, C, D, E, F, G: 2 - 406 (UniProt: Q8TDW0)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 1 | - | expression tag |
| Gly 205 | Asp 205 | variant |
| Ile 400 | Leu 400 | engineered mutation |
| Ala 402 | Gln 402 | engineered mutation |
| Ala 403 | Leu 403 | engineered mutation |
| Glu 404 | Asn 404 | engineered mutation |
| Lys 406 | Asn 406 | engineered mutation |
| Ala 407 | - | expression tag |
| Leu 408 | - | expression tag |
| Glu 409 | - | expression tag |
| Val 410 | - | expression tag |
| Leu 411 | - | expression tag |
| Phe 412 | - | expression tag |
| Gln 413 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 334039.6 | |
| All* | Total formula weight | 334039.6 |
