3BWY

Crystal Structure of Human 108M Catechol O-methyltransferase bound with S-adenosylmethionine and inhibitor dinitrocatechol

Summary for 3BWY

Entry DOI	10.2210/pdb3bwy/pdb
Descriptor	COMT protein, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... (6 entities in total)
Functional Keywords	comt, methyltransferase, polymorphism, rossmann fold, sam, dnc, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	24857.83
Authors	Rutherford, K.,Le Trong, I.,Stenkamp, R.E.,Parson, W.W. (deposition date: 2008-01-10, release date: 2008-06-03, Last modification date: 2023-08-30)
Primary citation	Rutherford, K.,Le Trong, I.,Stenkamp, R.E.,Parson, W.W. Crystal structures of human 108V and 108M catechol O-methyltransferase. J.Mol.Biol., 380:120-130, 2008 Cited by PubMed: 18486144 DOI: 10.1016/j.jmb.2008.04.040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation