3BWY
Crystal Structure of Human 108M Catechol O-methyltransferase bound with S-adenosylmethionine and inhibitor dinitrocatechol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | COMT protein | polymer | 214 | 23880.5 | 1 | UniProt (Q6ICE6) Pfam (PF01596) UniProt (by SIFTS) (P21964) | Homo sapiens (human) | (Catechol-O-methyltransferase, isoform CRA_a |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | D (A) | 3,5-DINITROCATECHOL | non-polymer | 200.1 | 1 | Chemie (DNC) | |||
| 5 | E, F, G (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 6 | H (A) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23880.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 977.4 | |
| All* | Total formula weight | 24857.8 |
