1WT7

Solution structure of BuTX-MTX: a butantoxin-maurotoxin chimera

Summary for 1WT7

• Entry DOI: 10.2210/pdb1wt7/pdb
• NMR Information: BMRB: 6389
• Descriptor: BuTX-MTX (1 entity in total)
• Functional Keywords: maurotoxin, butantoxin, scorpion toxin, k+ channels, molecular contacts, toxin affinity, toxin
• Cellular location: Secreted: P80719
• Total number of polymer chains: 1
• Total formula weight: 4434.24

Authors

M'Barek, S.,Chagot, B.,Andreotti, N.,Visan, V.,Mansuelle, P.,Grissmer, S.,Marrakchi, M.,El Ayeb, M.,Sampieri, F.,Darbon, H.,Fajloun, Z.,De Waard, M.,Sabatier, J.-M. (deposition date: 2004-11-16, release date: 2004-11-30, Last modification date: 2022-03-02)

• Primary citation: M'Barek, S.,Chagot, B.,Andreotti, N.,Visan, V.,Mansuelle, P.,Grissmer, S.,Marrakchi, M.,El Ayeb, M.,Sampieri, F.,Darbon, H.,Fajloun, Z.,De Waard, M.,Sabatier, J.M.; Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.; Proteins, 60:401-411, 2005; PubMed: 15971207; DOI: 10.1002/prot.20509

Experimental method

SOLUTION NMR